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We present a 60-year-old patient, admitted to the hospital presenting progressively with dysuria for more than 1 year, accompanied by frequent urination, urgent pain, and urinary retention, intermittent fever for 20 days. A multi-parametric magnetic resonance imaging (mpMRI) scan of the abdomen\/pelvis showed a prostatic abscess. Initially, meropenem treatment was not effective. Subsequently, the patient underwent an artificial intelligence-assisted mpMRI-TRUS (transrectal ultrasonography) real-time-guided puncture drainage. The results of purulent drainage cultures were positive for K. pneumonia, sensitive to bacillosporin. Thus, the combination treatment of sensitive antibiotics and transperineal drainage was conducted. The patient was followed up for 6 months, the outcome was satisfactory. Timely and appropriate treatments (such as the combination of sensitive antibiotics and artificial intelligence-assisted mpMRI-TRUS real-time-guided transperineal puncture drainage) are crucial for both patient survival and the prevention of complications. <\/jats:p>","DOI":"10.1177\/2050313x241301860","type":"journal-article","created":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T04:56:13Z","timestamp":1732164973000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["A rare case report of severe prostate abscess treated with artificial intelligence-assisted mpMRI-TRUS real-time-guided puncture drainage"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0810-0026","authenticated-orcid":false,"given":"Ye","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Urology, The First Affiliated Hospital of Hunan Normal University\/Hunan Provincial 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