{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:21:31Z","timestamp":1777418491524,"version":"3.51.4"},"reference-count":6,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p> Morbihan\u2019s disease is a rare form of facial lymphedema often associated with chronic rosacea and other skin diseases such as acne. It presents as indurated erythematous plaques in the upper face, which can be challenging to treat. We report a 69-year-old male of Asian background with a 4-year history of facial swelling and redness, unresponsive to prior treatments. After a clinical diagnosis of Morbihan\u2019s disease, the patient was treated with oral isotretinoin 10 mg daily, leading to an 80% reduction in symptoms after 9 months. Mild side effects, including cheilitis and xerosis, were well managed. This case highlights low-dose isotretinoin\u2019s potential as a therapeutic option for Morbihan\u2019s disease. Previous studies have demonstrated the efficacy of treating Morbihan\u2019s disease with isotretinoin at high doses between 40 and 80 mg po daily for 12\u201324 months. <\/jats:p>","DOI":"10.1177\/2050313x251320214","type":"journal-article","created":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T12:32:23Z","timestamp":1740400343000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Low-dose isotretinoin for the treatment of Morbihan\u2019s disease in a 69-year-old Asian male: A case report"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7764-3229","authenticated-orcid":false,"given":"Orhan","family":"Yilmaz","sequence":"first","affiliation":[{"name":"College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reetesh","family":"Bose","sequence":"additional","affiliation":[{"name":"Division of Dermatology, The Ottawa Hospital, Ottawa, ON Canada"},{"name":"Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4297-2337","authenticated-orcid":false,"given":"Sophia","family":"Colantonio","sequence":"additional","affiliation":[{"name":"Division of Dermatology, The Ottawa Hospital, Ottawa, ON Canada"},{"name":"Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,2,24]]},"reference":[{"issue":"10","key":"bibr1-2050313X251320214","first-page":"22","volume":"16","author":"van der Linden MM","year":"2023","journal-title":"J Clin Aesthet Dermatol"},{"key":"bibr2-2050313X251320214","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2008.02892.x"},{"key":"bibr3-2050313X251320214","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20174485"},{"key":"bibr4-2050313X251320214","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0000000000001589"},{"key":"bibr5-2050313X251320214","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2012.3109"},{"issue":"1","key":"bibr6-2050313X251320214","first-page":"32","volume":"12","author":"Olvera-Cort\u00e9s V","year":"2019","journal-title":"J Clin Aesthet Dermatol"}],"container-title":["SAGE Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X251320214","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X251320214","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X251320214","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T09:20:42Z","timestamp":1747992042000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X251320214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":6,"alternative-id":["10.1177\/2050313X251320214"],"URL":"https:\/\/doi.org\/10.1177\/2050313x251320214","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"value":"2050-313X","type":"print"},{"value":"2050-313X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"article-number":"2050313X251320214"}}