{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T15:55:30Z","timestamp":1769183730919,"version":"3.49.0"},"reference-count":30,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Sage Open Medical Case Reports"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:p>Non-lupus full-house nephropathy describes a pattern of \u201cfull-house\u201d immunofluorescence on renal biopsy in the absence of clinical or serologic markers for systemic lupus erythematosus. It is a rare disease with a broad range of etiologies, including idiopathic, secondary, or a prodrome of systemic lupus erythematosus. Current treatment options are lacking, with mixed results in the literature for varied immunosuppressive regimens. Rituximab, a selective anti-CD20 B-cell monoclonal antibody, has shown success in immune-complex mediated glomerular diseases but has not been commonly used or studied in non-lupus full-house nephropathy. Here, we present a case of non-lupus full-house nephropathy that was refractory to first-line immunosuppressants, in which two rounds of rituximab treatment achieved a positive response. This case emphasizes the need for systemic analysis of rituximab use in non-lupus full-house nephropathy, particularly given its mixed etiologies and presentations.<\/jats:p>","DOI":"10.1177\/2050313x251333979","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T03:33:33Z","timestamp":1747107213000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Rituximab treatment in non-lupus full-house nephropathy: A case report"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3704-9353","authenticated-orcid":false,"given":"Caroline","family":"Gee","sequence":"first","affiliation":[{"name":"Division of Nephrology, Hypertension and Kidney Transplantation, University of California, Irvine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dao","family":"Le","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Hypertension and Kidney Transplantation, University of California, Irvine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6517-041X","authenticated-orcid":false,"given":"Matthew D.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Hypertension and Kidney Transplantation, University of California, Irvine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Sisk","sequence":"additional","affiliation":[{"name":"Division of Pathology and Laboratory Medicine, University of California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramy","family":"Hanna","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Hypertension and Kidney Transplantation, University of California, Irvine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,5,13]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3109\/0886022X.2010.510614"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V102413"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.8886"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.40930"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfx020"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.0000000000000438"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfr663"},{"issue":"7","key":"e_1_3_2_9_2","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1093\/ndt\/gfw230","article-title":"Outcome of childhood-onset full-house nephropathy","volume":"32","author":"Ruggiero B","year":"2017","unstructured":"Ruggiero B, Vivarelli M, Gianviti A, et al. Outcome of childhood-onset full-house nephropathy. Nephrol Dial Transplant 2017; 32(7): 1194\u20131204.","journal-title":"Nephrol Dial Transplant"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.4103\/1319-2442.336762"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V7122518"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5002628"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.2174\/1389201003379059"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.04030808"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000071511.35221.B3"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.05231008"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/2180508"},{"issue":"4","key":"e_1_3_2_18_2","first-page":"471","article-title":"Late onset systemic lupus erythematosus and lupus-like disease in patients with apparent idiopathic glomerulonephritis","volume":"52","author":"Adu D","year":"1983","unstructured":"Adu D, Williams DG, Taube D, et al. Late onset systemic lupus erythematosus and lupus-like disease in patients with apparent idiopathic glomerulonephritis. QJM 1983; 52(4): 471\u2013487.","journal-title":"QJM"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004670050681"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1590\/2175-8239-jbn-2019-0242"},{"issue":"3","key":"e_1_3_2_21_2","first-page":"124","article-title":"Non-lupus \u201cfull house\u201d nephropathy, clinical and histological aspects. Experience in two hospitals in Medell\u00edn, Colombia","volume":"19","author":"Mart\u00edn Mar\u00edn L","year":"2012","unstructured":"Mart\u00edn Mar\u00edn L, Mu\u00f1oz Grajales C, Eraso Garnica R, et al. Non-lupus \u201cfull house\u201d nephropathy, clinical and histological aspects. Experience in two hospitals in Medell\u00edn, Colombia. Rev Colomb Reumatol 2012; 19(3): 124\u2013130.","journal-title":"Rev Colomb Reumatol"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1108178"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2020050683"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2020050699"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2020060802"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2021.02.002"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfae069.336"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.029694"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-202844"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1097\/MJT.0000000000001220"},{"key":"e_1_3_2_31_2","unstructured":"Hanif N Anwer F. Rituximab. 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