{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T07:59:32Z","timestamp":1782979172137,"version":"3.54.5"},"reference-count":15,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T00:00:00Z","timestamp":1748044800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T00:00:00Z","timestamp":1748044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Sage Open Medical Case Reports"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:p>Axial spondyloarthritis (axSpA) is a chronic inflammatory arthritis affecting the spine and sacroiliac joints, often accompanied by extra-musculoskeletal manifestations involving the eyes, gut, and skin. Other organ systems, including the heart (aortic insufficiency), lungs (upper-lobe predominant interstitial fibrosis), and kidneys (nephritic syndrome), may also be affected. Immunoglobulin A vasculitis (IgAV), formerly known as Henoch\u2013Sch\u00f6nlein purpura, is the most common systemic vasculitis in children and is typically self-limited. It is characterized by palpable purpura, arthritis or arthralgia, abdominal pain, and renal involvement. Studies suggest a potential link between elevated serum immunoglobulin A levels and active inflammation in axial spondyloarthritis. Here, we present a case of a Caucasian male diagnosed with immunoglobulin A vasculitis, leading to the identification of previously unrecognized axial spondyloarthritis. In addition, we reviewed the current literature on IgAV occurring in patients with axial spondyloarthritis.<\/jats:p>","DOI":"10.1177\/2050313x251341130","type":"journal-article","created":{"date-parts":[[2025,5,25]],"date-time":"2025-05-25T02:07:36Z","timestamp":1748138856000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["A case and literature review of axial spondyloarthritis and immunoglobulin A vasculitis: Rare association or under-recognized?"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0953-4669","authenticated-orcid":false,"given":"Robin","family":"Sia","sequence":"first","affiliation":[{"name":"Department of Rheumatology, The Northern Hospital, Epping, Victoria, Australia"},{"name":"Faculty of Medicine and Health, University of Sydney, Camperdown, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mueed","family":"Mian","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, The Northern Hospital, Epping, Victoria, Australia"},{"name":"Epping Specialist Group, Epping, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,5,24]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24266"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2017-212076"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2021-221035"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2017.188"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02668"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60635-7"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.39.6.545"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.49.8.638"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.52.1.61"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.2340\/0001555577324"},{"issue":"4","key":"e_1_3_2_12_2","article-title":"Leukocytoclastic vasculitis in a patient with ankylosing spondylitis","volume":"12","author":"Kobak S","year":"2014","unstructured":"Kobak S, Yilmaz H, Karaarslan A, et al. Leukocytoclastic vasculitis in a patient with ankylosing spondylitis. Case Rep Rheumatol 2014; 12(4): e8769.","journal-title":"Case Rep Rheumatol"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2018-228881"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2022-252182"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2024.105723"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.1072453"}],"container-title":["Sage Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X251341130","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X251341130","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X251341130","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:19:28Z","timestamp":1767676768000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X251341130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,24]]},"references-count":15,"alternative-id":["10.1177\/2050313X251341130"],"URL":"https:\/\/doi.org\/10.1177\/2050313x251341130","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"value":"2050-313X","type":"print"},{"value":"2050-313X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,24]]},"article-number":"2050313X251341130"}}