{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:28:30Z","timestamp":1767677310210,"version":"3.48.0"},"reference-count":11,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Sage Open Medical Case Reports"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:p>Zinc deficiency can be inherited, such as in the case of acrodermatitis enteropathica or acquired. In both cases, patients will present typical acral and periorificial skin lesions, and seldom, diarrhea as well as secondary alopecia. In this report, we provide a case of transient neonatal zinc deficiency in a 3-month-old breastfed girl who presented with classical skin lesions of zinc deficiency. The diagnosis was determined following the results of blood tests, which indicated a combination of low plasma phosphatase alkaline and zinc levels. To support the diagnosis, genetic testing was performed on the mother to detect a mutation in the SLC30A2 gene. However, the results were inconclusive as a variant of unknown significance was found. After starting zinc supplementation, the skin lesions completely resolved a few weeks later without any recurrence.<\/jats:p>","DOI":"10.1177\/2050313x251341516","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T05:04:02Z","timestamp":1747112642000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Transient neonatal zinc deficiency in a 3-month-old infant: A case report"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-0145-7443","authenticated-orcid":false,"given":"Damy","family":"Horth","sequence":"first","affiliation":[{"name":"Department of Dermatology, Universit\u00e9 Laval, Qu\u00e9bec, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Auger","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Universit\u00e9 Laval, Qu\u00e9bec, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,5,13]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2016.108"},{"issue":"10","key":"e_1_3_2_3_2","first-page":"487","article-title":"Altered expression of two zinc transporters, SLC30A5 and SLC30A6, underlies a mammary gland disorder of reduced zinc secretion into milk","volume":"38","author":"Kumar L","year":"2015","unstructured":"Kumar L, Michalczyk A, McKay J, et al. Altered expression of two zinc transporters, SLC30A5 and SLC30A6, underlies a mammary gland disorder of reduced zinc secretion into milk. Genes Nutr 2015; 38(10): 487.","journal-title":"Genes Nutr"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1039\/C7MT00162B"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.08.015"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/humu.20988"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12257"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.3177\/jnsv.61.S44"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu10101438"},{"key":"e_1_3_2_10_2","first-page":"591","volume-title":"Pediatric nutrition","author":"American Academy of Pediatrics Committee on Nutrition","year":"2019","unstructured":"American Academy of Pediatrics Committee on Nutrition. Trace elements. In: Kleinman RE, Greer FR (eds.) Pediatric nutrition. 8th ed. 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