{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:28:44Z","timestamp":1767677324828,"version":"3.48.0"},"reference-count":11,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Sage Open Medical Case Reports"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:p>Extramammary Paget\u2019s disease is a rare cutaneous malignancy that typically presents as carcinoma in situ, and instances of invasive extramammary Paget\u2019s disease are exceptionally rare. Herein, we describe a rare case of invasive extramammary Paget\u2019s disease of the scrotum. A 91-year-old male presented with an over 10-year history of a granulomatous rash with serous discharge, refractory to various topical therapies and weekly wound care. Physical examination revealed a well-demarcated, erythematous, mamillated, eroded plaque with arcuate borders involving the left inguinal crease and scrotum. A punch biopsy showed intra-epidermal and invasive carcinoma with focal pagetoid spread and intracytoplasmic mucin. The favored diagnosis was primary, invasive extramammary Paget\u2019s disease. The patient underwent a wide local excision and routine imaging surveillance and remains recurrence-free at 1-year follow-up. Given that extramammary Paget\u2019s disease remains commonly misdiagnosed, leading to delays in treatment, dermatologists should be aware of this diagnosis, particularly for elderly patients presenting with non-specific genital lesions recalcitrant to routine treatment.<\/jats:p>","DOI":"10.1177\/2050313x251350334","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T05:08:48Z","timestamp":1751951328000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Invasive extramammary Paget\u2019s disease of the scrotum: A case report"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6495-088X","authenticated-orcid":false,"given":"Heidi Oi-Yee","family":"Li","sequence":"first","affiliation":[{"name":"Division of Dermatology, The Ottawa Hospital, University of Ottawa, ON, Canada"},{"name":"Faculty of Medicine, University of Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alicia","family":"Van","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Lipson","sequence":"additional","affiliation":[{"name":"Division of Dermatology, The Ottawa Hospital, University of Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,7,8]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2012.01.032"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol28040260"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2021.7148"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.dad.0000158291.20440.13"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.dad.0000194052.65695.f1"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.5070\/D3254043591"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000002064"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.53.10.742"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13833"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2010.08.002"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000002240"}],"container-title":["Sage Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X251350334","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X251350334","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X251350334","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:20:22Z","timestamp":1767676822000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X251350334"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,8]]},"references-count":11,"alternative-id":["10.1177\/2050313X251350334"],"URL":"https:\/\/doi.org\/10.1177\/2050313x251350334","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"type":"print","value":"2050-313X"},{"type":"electronic","value":"2050-313X"}],"subject":[],"published":{"date-parts":[[2025,7,8]]},"article-number":"2050313X251350334"}}