{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:28:32Z","timestamp":1767677312384,"version":"3.48.0"},"reference-count":19,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Sage Open Medical Case Reports"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:p>Inherited reticulate pigmentary disorders (IRPD) are a group of rare dermatologic conditions characterized by distinct reticulate patterns of hyperpigmentation and\/or hypopigmentation of the skin. These conditions are considered genodermatoses caused by genetic mutations that are often inherited in affected families. IRPDs exhibit considerable phenotypic variability, ranging from having minimal or no systemic involvement to profound associations with neurocognitive, immunologic, and other organ abnormalities. Here, we discuss a rare case of dyschromatosis symmetrica hereditaria in an otherwise healthy 6-year-old boy. In this report, we aim to present the clinical manifestations of one subtype of reticulate pigmentary genodermatosis that, although uncommon in regions like Canada, immigration from other parts of the world, like Asia, highlights the need for awareness among Canadian physicians.<\/jats:p>","DOI":"10.1177\/2050313x251358966","type":"journal-article","created":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T05:06:36Z","timestamp":1754024796000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A rare presentation of dyschromatosis symmetrica hereditaria in a Canadian context: A case report"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-1048-6181","authenticated-orcid":false,"given":"Sonia","family":"Czyz","sequence":"first","affiliation":[{"name":"Department of Medicine, University of Calgary, Calgary, AB, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatemeh","family":"Jafarian","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, University of Calgary, Calgary, AB, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Holfeld","sequence":"additional","affiliation":[{"name":"Division of Dermatology, College of Medicine, University of Saskatchewan, Regina, SK, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,7,31]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"95","article-title":"Dyschromatosis symmetrica heridetaria","volume":"29","author":"Toyama I","year":"1929","unstructured":"Toyama I. 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Case report: aicardi-gouti\u00e8res syndrome type 6 and dyschromatosis symmetrica hereditaria with congenital heart disease and mitral valve calcification \u2013 phenotypic variants caused by adenosine deaminase acting on the RNA 1 gene homozygous mutations. 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