{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T07:01:42Z","timestamp":1769410902428,"version":"3.49.0"},"reference-count":17,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Sage Open Medical Case Reports"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Pertussis, caused by\n                    <jats:italic toggle=\"yes\">Bordetella pertussis<\/jats:italic>\n                    , is increasingly recognized in adults who often present with atypical symptoms, leading to underdiagnosis. We report a case of a 64-year-old woman with a persistent cough and sore throat initially treated as refractory community-acquired pneumonia. Despite empirical antibiotic therapy, her symptoms persisted. Conventional diagnostic tests, including sputum and bronchoalveolar lavage fluid cultures, were negative. Metagenomic next-generation sequencing of bronchoalveolar lavage fluid identified\n                    <jats:italic toggle=\"yes\">Bordetella pertussis<\/jats:italic>\n                    with high sequence coverage (7497 reads). The patient showed no clinical improvement with azithromycin, prompting a switch to trimethoprim\u2013sulfamethoxazole, after which she improved and was discharged to complete a 14-day course. At 1-month follow-up, she was asymptomatic with resolved radiographic findings. This case highlights that pertussis can mimic refractory pneumonia in adults without typical features such as whooping cough, and underscores the diagnostic value of metagenomic next-generation sequencing when conventional methods fail. Clinicians should consider pertussis in adults with prolonged cough unresponsive to standard community-acquired pneumonia therapy and be aware of potential macrolide resistance, which may necessitate alternative antibiotics like trimethoprim\u2013sulfamethoxazole.\n                  <\/jats:p>","DOI":"10.1177\/2050313x251411124","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T15:59:57Z","timestamp":1767887997000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Pertussis is identified among common respiratory diseases: A case report"],"prefix":"10.1177","volume":"14","author":[{"given":"Jiajia","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, The People\u2019s Hospital of Rongchang District, Chongqing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongchang","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, The People\u2019s Hospital of Rongchang District, Chongqing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiamei","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, The People\u2019s Hospital of Rongchang District, Chongqing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiguang","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Nephrology, The People\u2019s Hospital of Rongchang District, Chongqing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6194-4767","authenticated-orcid":false,"given":"Yu","family":"Zhai","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, The People\u2019s Hospital of Rongchang District, Chongqing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,1,8]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2025.2513729"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvacx.2021.100103"},{"key":"e_1_3_3_4_2","first-page":"4786141","article-title":"Pertussis reinfection in an adult: a cause of persistent cough not to be ignored","volume":"2017","author":"Koufakis T","year":"2017","unstructured":"Koufakis T, Paschala A, Siapardanis D. Pertussis reinfection in an adult: a cause of persistent cough not to be ignored. Case Rep Infect Dis 2017; 2017: 4786141.","journal-title":"Case Rep Infect Dis"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2023.12.020"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6903a5"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11111570"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.942672"},{"issue":"1","key":"e_1_3_3_9_2","doi-asserted-by":"crossref","DOI":"10.1378\/chest.129.1_suppl.75S","article-title":"Chronic cough due to asthma\u2014ACCP evidence-based clinical practice guidelines","volume":"129","author":"Dicpinigaitis PV.","year":"2006","unstructured":"Dicpinigaitis PV. Chronic cough due to asthma\u2014ACCP evidence-based clinical practice guidelines. Chest 2006; 129(1): 75S\u201379S.","journal-title":"Chest"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-024-10108-6"},{"issue":"7","key":"e_1_3_3_11_2","first-page":"65","article-title":"Etiological diagnosis and treatment value of mNGS in alveolar lavage fluid of children with severe pneumonia","volume":"30","author":"Chen W","year":"2024","unstructured":"Chen W, Zhou H. Etiological diagnosis and treatment value of mNGS in alveolar lavage fluid of children with severe pneumonia. Altern Ther Health Med 2024; 30(7): 65\u201371.","journal-title":"Altern Ther Health Med"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2024.29.49.2400765"},{"key":"e_1_3_3_13_2","first-page":"26","volume-title":"Pertussis: Epidemiology, immunology, and evolution","author":"Skarlupka AL","year":"2019","unstructured":"Skarlupka AL, Linz B, Maynard J, et al. Basics of pertussis pathogenesis. In: Rohani P, Scarpino SV (eds.) Pertussis: Epidemiology, immunology, and evolution. Oxford University Press, 2019, pp.26\u201341."},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3235"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1183\/20734735.0099-2024"},{"issue":"3","key":"e_1_3_3_16_2","volume":"4","author":"Nieves DJ","year":"2016","unstructured":"Nieves DJ, Heininger U. Bordetella pertussis. Microbiol Spectr 2016; 4(3): e10.","journal-title":"Bordetella pertussis. 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