{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T09:01:44Z","timestamp":1771146104787,"version":"3.50.1"},"reference-count":16,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Sage Open Medical Case Reports"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Ceruminous adenocarcinoma (CAC) represents an exceedingly rare malignant glandular neoplasm originating from the ceruminous glands within the external auditory canal (EAC), constituting approximately 5%\u201310% of all EAC malignancies. Owing to its insidious onset and nonspecific symptoms, diagnosis is frequently delayed. This report delineates a case of right EAC CAC in a 39-year-old male, focusing on the diagnostic trajectory, multimodal therapy, and short-term outcomes. The patient presented with a one-month history of recurrent bloody purulent discharge from the right ear, intermittent otalgia, and mild conductive hearing loss. Otoscopy revealed a cauliflower-like, ulcerated, and bleeding mass on the floor of the right EAC. Computed tomography (CT) showed a mass within the right EAC encroaching upon the superficial parotid lobe and the facial nerve\u2019s vertical segment, with no intracranial extension. Cervical ultrasound demonstrated multiple enlarged lymph nodes in right levels 2\u20134. A pathological biopsy confirmed CAC, with immunohistochemical staining positive for CK7, EMA, and partially for S-100. The patient underwent radical surgery, including right subtotal temporal bone resection (with EAC and mastoid removal, reconstructed using temporalis fascia and a skin graft), right total parotidectomy, and right cervical level 2\u20134 lymph node dissection. Intraoperatively, the tumor infiltrated the facial nerve sheath, but the nerve parenchyma was preserved; the sheath was dissected free without nerve resection or anastomosis. Postoperative adjuvant radiotherapy (60 Gy in 30 fractions) was administered. Recovery was uneventful. At 3-month follow-up, the EAC wound had healed completely, and CT\/magnetic resonance imaging showed no residual or recurrent tumor.<\/jats:p>","DOI":"10.1177\/2050313x261420024","type":"journal-article","created":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T10:49:19Z","timestamp":1770979759000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A case report of ceruminous adenocarcinoma of the external auditory canal"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-4410-9546","authenticated-orcid":false,"given":"Liang","family":"Luo","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Ganzhou People\u2019s Hospital, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Ganzhou People\u2019s Hospital, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin-Tao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Ganzhou People\u2019s Hospital, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Long-Gui","family":"You","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Ganzhou People\u2019s Hospital, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3878-0973","authenticated-orcid":false,"given":"Huan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Ganzhou People\u2019s Hospital, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Yanping","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Ganzhou People\u2019s Hospital, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,2,13]]},"reference":[{"issue":"10","key":"e_1_3_2_2_2","first-page":"1733","article-title":"Tumors of the ceruminous glands of the external auditory canal","volume":"82","author":"Wetli CV","year":"1972","unstructured":"Wetli CV, Gacek RR, Sofferman RA, et al. 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J Guiyang Med Coll (Guiyang Yi Xue Yuan Xue Bao) 2001; 26(3): 281.","journal-title":"J Guiyang Med Coll (Guiyang Yi Xue Yuan Xue Bao)"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-017-0484-y"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nec.2012.08.009"},{"key":"e_1_3_2_11_2","first-page":"217","volume-title":"Salivary gland diseases","author":"Ma DQ.","year":"2002","unstructured":"Ma DQ. Salivary gland diseases. People\u2019s Medical Publishing House, 2002, pp. 217\u2013220."},{"issue":"2","key":"e_1_3_2_12_2","first-page":"147","article-title":"Clinical analysis of 41 cases of parotid gland cancer","volume":"16","author":"Li YG","year":"1997","unstructured":"Li YG, Zhu YC. Clinical analysis of 41 cases of parotid gland cancer. Ai Zheng 1997; 16(2): 147\u2013149.","journal-title":"Ai Zheng"},{"issue":"4","key":"e_1_3_2_13_2","first-page":"582","article-title":"Squamous cell carcinoma of the external auditory canal: an evaluation of a staging system","volume":"21","author":"Moody SA","year":"2000","unstructured":"Moody SA, Hirsch BE, Myers EN. Squamous cell carcinoma of the external auditory canal: an evaluation of a staging system. Am J Otol 2000; 21(4): 582\u2013588.","journal-title":"Am J Otol"},{"issue":"1","key":"e_1_3_2_14_2","first-page":"112","article-title":"External auditory canal ceruminous adenocarcinoma presenting as a polypoid mass","volume":"13","author":"Bilici S","year":"2017","unstructured":"Bilici S, Dilek SF, Yigit O, et al. External auditory canal ceruminous adenocarcinoma presenting as a polypoid mass. 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