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With an estimated annual incidence of approximately three cases per million individuals, the condition is associated with a significantly increased risk of cardiovascular complications, such as arrhythmias and acromegaly-induced cardiomyopathy. Heart failure secondary to acromegalic cardiomyopathy occurs in approximately 3% of affected patients and is recognized as the leading cause of mortality in individuals with this condition. This case report describes a 53-year-old male diagnosed with acromegalic cardiomyopathy caused by a pituitary adenoma.<\/jats:p>","DOI":"10.1177\/2050313x261420035","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T12:57:31Z","timestamp":1770901051000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Acromegaly-induced dilated cardiomyopathy presenting with heart failure as the cardinal symptom: A case report"],"prefix":"10.1177","volume":"14","author":[{"given":"Jiamin","family":"Xu","sequence":"first","affiliation":[{"name":"Cardiovascular Disease Center, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi Clinical College of Wuhan University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Liu","sequence":"additional","affiliation":[{"name":"Cardiovascular Disease Center, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi Clinical College of Wuhan University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heng","family":"Wu","sequence":"additional","affiliation":[{"name":"Cardiovascular Disease Center, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi Clinical College of Wuhan University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqin","family":"Zhu","sequence":"additional","affiliation":[{"name":"Cardiovascular Disease Center, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi Clinical College of Wuhan University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5384-9388","authenticated-orcid":false,"given":"Jiaxin","family":"Hu","sequence":"additional","affiliation":[{"name":"Cardiovascular Disease Center, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi Clinical College of Wuhan University, China"},{"name":"Hubei Selenium and Human Health Institute, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,2,12]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(22)00244-3"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-024-00993-x"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-019-0071-6"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11102-017-0797-7"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.577173"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eprac.2024.09.014"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00120"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2023.102921"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1210\/er.2003-0009"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.598948"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw128"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14061906"},{"issue":"1","key":"e_1_3_2_14_2","first-page":"31","article-title":"Acromegalic cardiomyopathy: a neglected cause of cardiomyopathy","volume":"173","author":"Bonora T","year":"2022","unstructured":"Bonora T, Rigamonti E, Capoferri M, et al. 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