{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T08:03:20Z","timestamp":1779696200347,"version":"3.53.1"},"reference-count":18,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100019779","name":"Qatar National Library","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019779","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Sage Open Medical Case Reports"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Acromegaly is a rare endocrine disorder with an insidious onset and delayed diagnosis, and emerging evidence suggests a potential link to an increased risk of thromboembolic and cerebrovascular events. We present three cases where vascular events were the initial or incidental diagnostic clue.\n                    <jats:italic toggle=\"yes\">Case 1<\/jats:italic>\n                    involves a 52-year-old man with pulmonary embolism who was subsequently diagnosed with acromegaly.\n                    <jats:italic toggle=\"yes\">Case 2<\/jats:italic>\n                    describes a 30-year-old man with bilateral pulmonary embolism and a delayed diagnosis of acromegaly.\n                    <jats:italic toggle=\"yes\">Case 3<\/jats:italic>\n                    reports a 44-year-old man who presented with a transient ischemic attack, leading to the incidental discovery of a pituitary microadenoma and a diagnosis of acromegaly. All patients showed a clinical or biochemical response to therapy. These cases highlight the importance of considering acromegaly in patients with unexplained thromboembolic or cerebrovascular events, as early diagnosis and treatment are crucial for reducing long-term morbidity.\n                  <\/jats:p>","DOI":"10.1177\/2050313x261438398","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T12:55:41Z","timestamp":1779454541000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Thromboembolic and cerebrovascular events as initial clues to acromegaly: A clinical case series and review of pathophysiologic links"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9330-5740","authenticated-orcid":false,"given":"Elabbass A.","family":"Abdelmahmuod","sequence":"first","affiliation":[{"name":"Endocrine Section, Department of Medicine, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarik","family":"Elhadd","sequence":"additional","affiliation":[{"name":"Endocrine Section, Department of Medicine, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,22]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1590\/2359-3997000000195"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-1668"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-15-0189"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11102-015-0655-4"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-14-0144"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014-2700"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1510439"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11102-016-0754-x"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1071\/HC15033"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11102-015-0701-2"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1009965803750"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2015.11.026"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-007-9063-z"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-007-9062-0"},{"issue":"8","key":"e_1_3_3_16_2","first-page":"2730","article-title":"Mortality and cancer incidence in acromegaly: a retrospective cohort study. United Kingdom Acromegaly Study Group","volume":"83","author":"Orme SM","year":"1998","unstructured":"Orme SM, McNally RJQ, Cartwright RA, et al. Mortality and cancer incidence in acromegaly: a retrospective cohort study. United Kingdom Acromegaly Study Group. J Clin Endocrinol Metab 1998; 83(8): 2730\u20132734.","journal-title":"J Clin Endocrinol Metab"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2016.08.1442"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2015.12.005"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000211"}],"container-title":["Sage Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X261438398","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X261438398","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X261438398","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T07:16:37Z","timestamp":1779693397000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X261438398"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":18,"alternative-id":["10.1177\/2050313X261438398"],"URL":"https:\/\/doi.org\/10.1177\/2050313x261438398","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"value":"2050-313X","type":"print"},{"value":"2050-313X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"article-number":"2050313X261438398"}}