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The histological characteristics of leukocytoclastic vasculitis include neutrophil infiltration around small cutaneous blood arteries and fibrinoid necrotizing inflammation. Annular morphology is a unique and rare type of leukocytoclastic vasculitis. We report a case of annular leukocytoclastic vasculitis in a 39-year-old Saudi man who presented with scaly annular erythema and targetoid lesion configurations with prominent, raised borders. He was managed with oral prednisolone 40\u2009mg daily as a tapered dosage regimen, in combination with topical mometasone furoate 0.1% cream applied twice daily, resulting in complete resolution of lesions. To the best of our knowledge, this is the first reported case of annular morphology of leukocytoclastic vasculitis with microvascular occlusions in the Middle East.<\/jats:p>","DOI":"10.1177\/2050313x261440652","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T11:58:58Z","timestamp":1776254338000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Annular leukocytoclastic vasculitis associated with isolated anti-\u03b22 glycoprotein I immunoglobulin G positivity: A case report"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-6943-7968","authenticated-orcid":false,"given":"Saleha Abdulrahman","family":"Aldawsari","sequence":"first","affiliation":[{"name":"Department of Dermatology, King Fahad Hospital, Hofuf, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6334-780X","authenticated-orcid":false,"given":"Ajlan Hashim","family":"Alajlani","sequence":"additional","affiliation":[{"name":"College of Medicine, King Faisal University, Al-Ahsa, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1256-8632","authenticated-orcid":false,"given":"Abdulelah Nabil","family":"Alkadi","sequence":"additional","affiliation":[{"name":"College of Medicine, King Faisal University, Al-Ahsa, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3373-7327","authenticated-orcid":false,"given":"Sadeq Wasil","family":"Al-Dandan","sequence":"additional","affiliation":[{"name":"Anatomical Pathology Unit, Department of Laboratory and Blood Bank, King Fahad Hospital, Hofuf, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,15]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.40375"},{"issue":"5","key":"e_1_3_2_3_2","article-title":"Annular leukocytoclastic vasculitis: a new feature of IgA vasculitis","volume":"11","author":"Belfeki N","year":"2024","unstructured":"Belfeki N, Ghriss N, Kammoun S, et al. Annular leukocytoclastic vasculitis: a new feature of IgA vasculitis. 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