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This report describes the clinical course of a patient with severe lower-limb paralysis caused by encephalomyeloradiculoneuropathy. A man in his 50s developed a fever, impaired consciousness, and respiratory failure requiring mechanical ventilation. Based on the combined involvement of the central and peripheral nervous systems, a clinical diagnosis of encephalomyeloradiculoneuropathy was made. Rehabilitation treatment was initiated early during mechanical ventilation in the acute-care hospital, at a time when he required total assistance for ambulation. Despite immunotherapy, near-complete paralysis of the trunk and bilateral lower limbs persisted with orthostatic hypotension. Rehabilitation treatment was continued in acute-care and rehabilitation hospitals with monthly goal setting. At 8\u2009months, he achieved independent outdoor ambulation.<\/jats:p>","DOI":"10.1177\/2050313x261456977","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T03:33:45Z","timestamp":1781494425000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Recovery of functional ambulation through stepwise rehabilitation treatment in a patient with encephalomyeloradiculoneuropathy: A case report"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1854-5052","authenticated-orcid":false,"given":"Koshiro","family":"Sawada","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan"},{"name":"Department of Rehabilitation, University Hospital, Kyoto Prefectural University of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fukiko","family":"Morii","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, University Hospital, Kyoto Prefectural University of Medicine, Japan"},{"name":"Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7829-7591","authenticated-orcid":false,"given":"Norikazu","family":"Hishikawa","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8701-0221","authenticated-orcid":false,"given":"Hiroshi","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Gakusai Hospital, Kyoto Interdisciplinary Institute of Community Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Iwasaki","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan"},{"name":"Department of Rehabilitation, Gakusai Hospital, Kyoto Interdisciplinary Institute of Community Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misaki","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Kojima","sequence":"additional","affiliation":[{"name":"Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Ohara","sequence":"additional","affiliation":[{"name":"Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo","family":"Mikami","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan"},{"name":"Department of Rehabilitation, University Hospital, Kyoto Prefectural University of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,14]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"114","article-title":"Anti-neutral glycolipid antibodies in encephalomyeloradiculoneuropathy (EMRN)","volume":"81","author":"Shima S","year":"2013","unstructured":"Shima S, Kawamura N, Ishikawa T, et al. 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