{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T05:11:55Z","timestamp":1783746715943,"version":"3.55.0"},"reference-count":10,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Sage Open Medical Case Reports"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Radiation-induced morphoea is an under-recognised complication of radiotherapy that can cause significant pain, functional impairment, and disfigurement. It is frequently misdiagnosed due to its non-specific presentation. We report the case of a 70-year-old female with prior right breast invasive ductal carcinoma, status post-lumpectomy, who developed painful cutaneous thickening and atrophy within the irradiated field 18\u2009months after adjuvant radiotherapy. Malignant recurrence was excluded, and biopsy revealed dermal sclerosis with collagen thickening consistent with radiation-induced morphoea. Management included intralesional corticosteroid injections, regional nerve blocks, and physical therapy. Early recognition, biopsy, and multidisciplinary management are critical to improving patients\u2019 quality of life.<\/jats:p>","DOI":"10.1177\/2050313x261463846","type":"journal-article","created":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T05:23:40Z","timestamp":1783574620000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Radiation-induced morphoea in the setting of previous breast cancer: A case report"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-7459-2116","authenticated-orcid":false,"given":"Sydney A.","family":"Yee","sequence":"first","affiliation":[{"name":"Department of Medicine, Cumming School of Medicine, University of Calgary, AB, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9863-5084","authenticated-orcid":false,"given":"David M.","family":"Langelier","sequence":"additional","affiliation":[{"name":"Division of Clinical Neurosciences, Department of Medicine, Cumming School of Medicine, University of Calgary, AB, Canada"},{"name":"Division of Oncology, Department of Medicine, Cumming School of Medicine, University of Calgary, AB, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyla","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, AB, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynne H.","family":"Robertson","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Cumming School of Medicine, University of Calgary, AB, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,8]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","unstructured":"Gonzalez-Ericsson PI Estrada MV Al-Rohil R et al. Post-irradiation morphoea of the breast: a case report and review of the literature. Histopathology 2018; 72(2): 342\u2013350. https:\/\/doi.org\/10.1111\/his.13343","DOI":"10.1111\/his.13343"},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","unstructured":"Partl R Regitnig P Lukasiak K et al. Incidence of morphea following adjuvant irradiation of the breast in 2 268 patients. Breast Care 2020; 15(3): 246\u2013252. https:\/\/doi.org\/10.1159\/000502030","DOI":"10.1159\/000502030"},{"key":"e_1_3_2_4_2","doi-asserted-by":"crossref","unstructured":"Ardern-Jones MR Black MM. Widespread morphoea following radiotherapy for carcinoma of the breast. Clin Exp Dermatol 2003; 28(2): 160\u2013162. https:\/\/doi.org\/10.1046\/j.1365-2230.2003.01186.x","DOI":"10.1046\/j.1365-2230.2003.01186.x"},{"key":"e_1_3_2_5_2","doi-asserted-by":"crossref","unstructured":"Spalek M Jonska-Gmyrek J Galecki J. Radiation-induced morphea \u2013 a literature review. 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Characteristics and treatment of postirradiation morphea: a retrospective multicenter analysis. J Am Acad Dermatol 2017; 76(1): 19\u201321. https:\/\/doi.org\/10.1016\/j.jaad.2016.08.059","DOI":"10.1016\/j.jaad.2016.08.059"},{"key":"e_1_3_2_9_2","doi-asserted-by":"crossref","unstructured":"Zwischenberger BA Jacobe HT. A systematic review of morphea treatments and therapeutic algorithm. J Am Acad Dermatol 2011; 65(5): 925\u2013941. https:\/\/doi.org\/10.1016\/j.jaad.2010.09.006","DOI":"10.1016\/j.jaad.2010.09.006"},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","unstructured":"Yuksel SS Chappell AG Jackson BT et al. Post mastectomy pain syndrome: a systematic review of prevention modalities. JPRAS Open 2022; 31: 32\u201349. https:\/\/doi.org\/10.1016\/j.jpra.2021.10.009","DOI":"10.1016\/j.jpra.2021.10.009"},{"key":"e_1_3_2_11_2","doi-asserted-by":"crossref","unstructured":"Shah JD Kirkpatrick K Shah K. 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