{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T04:08:58Z","timestamp":1748578138553,"version":"3.41.0"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["UEG Journal"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The current prevalence of esophagitis in southern Europe is unknown. In addition, the risk factors for reflux esophagitis are not fully understood.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The objective of this article is to assess the prevalence and risk factors for esophagitis in Spain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective, observational, cross\u2010sectional, multicenter study (PRESS study) was conducted among 31 gastrointestinal endoscopy units throughout Spain. A total of 1361 patients undergoing upper gastrointestinal endoscopy were enrolled. Sociodemographic, clinical and treatment data were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 95% of patients were Caucasian and 52% were male (mean age: 53\u2009\u00b1\u200917 years). The most frequent symptoms prompting endoscopy were heartburn (40%), regurgitation (26%) and dysphagia (15%). Fifty\u2010four percent of patients undergoing endoscopy were receiving proton pump inhibitor (PPI) treatment. Esophagitis (mainly mild\u2010moderate) was present in 154 (12.4%) patients. The severe form was recorded in only 11 (0.8%) patients. Multivariate analysis results indicated that the likelihood of esophagitis was higher in men (OR\u2009=\u20091.91, 95% CI\u2009=\u20091.31\u20132.78), in patients with high GERD\u2010Q scores (OR\u2009=\u20091.256, 95% CI\u2009=\u20091.176\u20131.343), weight increase (OR\u2009=\u20091.014, 95% CI\u2009=\u20091.003\u20131.025) and high alcohol consumption (OR\u2009=\u20092.49, 95% CI\u2009=\u20091.16\u20135.36).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Severe esophagitis is a rare finding in the Spanish population. Male gender, high GERD\u2010Q score, weight increase and high alcohol consumption are main risk factors for its appearance.<\/jats:p><\/jats:sec>","DOI":"10.1177\/2050640615595916","type":"journal-article","created":{"date-parts":[[2015,7,25]],"date-time":"2015-07-25T02:35:39Z","timestamp":1437791739000},"page":"229-235","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Prevalence of severe esophagitis in Spain. Results of the PRESS study (Prevalence and Risk factors for Esophagitis in Spain: A cross\u2010sectional study)"],"prefix":"10.1002","volume":"4","author":[{"given":"N\u00faria","family":"Piqu\u00e9","sequence":"first","affiliation":[{"name":"Department of Microbiology and Parasitology Pharmacy Faculty Universitat de Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Ponce","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hospital Universitario La Fe Valencia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vicente","family":"Garrigues","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hospital Universitario La Fe Valencia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Rodrigo","sequence":"additional","affiliation":[{"name":"Digestive Tract Department Hospital Central de Asturias Oviedo 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Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd) Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier P","family":"Gisbert","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd) Madrid Spain"},{"name":"Hospital Universitario de la Princesa Instituto de Investigaci\u00f3n Sanitaria Princesa (IIS\u2010IP) Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Suarez","sequence":"additional","affiliation":[{"name":"Unitat d\u2019Epidemiologia i Avaluaci\u00f3\u2010Fundaci\u00f3 Parc Taul\u00ed Hospital de Sabadell Institut Universitari Parc Taul\u00ed Universitat Aut\u00f3noma de Barcelona Sabadell Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Calvet","sequence":"additional","affiliation":[{"name":"Hospital Universitario de la 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