{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T20:57:21Z","timestamp":1783976241138,"version":"3.55.0"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["UEG Journal"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Several years ago the International Autoimmune Hepatitis Group simplified the previous <jats:italic>revised original scoring system<\/jats:italic> for diagnosis of autoimmune hepatitis (AIH) into a scoring system based on only four instead of 13 parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>We aimed to evaluate the suitability of the <jats:italic>simplified<\/jats:italic> AIH score for diagnosis of AIH in a German cohort with chronic liver diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this retrospective single\u2010center study, we compared the accuracy of both AIH scores in 70 patients with AIH and 211 patients with chronic liver diseases (PBC (<jats:italic>n<\/jats:italic> \u2009=\u200952), PSC (<jats:italic>n<\/jats:italic> \u2009=\u200927), NASH (<jats:italic>n<\/jats:italic> \u2009=\u200967), DILI (<jats:italic>n<\/jats:italic> \u2009=\u200915), CHB\/C (<jats:italic>n<\/jats:italic> \u2009=\u200950)). Sensitivity, specificity and predictability of each scoring system were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Using the <jats:italic>simplified<\/jats:italic> AIH score, the sensitivity and specificity of detecting a <jats:italic>probable<\/jats:italic> AIH (scores\u2009\u2265\u20096) were 96% and 97% with a positive and negative predictive value of 92% and 99%, respectively. For diagnosis of <jats:italic>definite<\/jats:italic> AIH (scores\u2009\u2265\u20097), the sensitivity and specificity were 43% and 100% with a positive and negative predictive value of 97% and 84%, respectively. The concordance with the <jats:italic>revised original<\/jats:italic> criteria was 63%. The specificity for excluding AIH was excellent in both scoring system.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The <jats:italic>simplified<\/jats:italic> diagnostic criteria allow a reliable diagnosis of AIH in a German cohort.<\/jats:p><\/jats:sec>","DOI":"10.1177\/2050640617711632","type":"journal-article","created":{"date-parts":[[2017,5,18]],"date-time":"2017-05-18T12:22:19Z","timestamp":1495110139000},"page":"247-254","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Suitability of the simplified autoimmune hepatitis score for the diagnosis of autoimmune hepatitis in a German cohort"],"prefix":"10.1002","volume":"6","author":[{"given":"Hella","family":"Wobser","sequence":"first","affiliation":[{"name":"University Hospital of Regensburg Department of Internal Medicine and Gastroenterology Regensburg 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