{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T13:27:04Z","timestamp":1792589224719,"version":"4.5.0"},"reference-count":28,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["UEG Journal"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Gastrointestinal symptoms can be triggered by food intake and psychological distress, but individual\u2010level research on food\u2013symptom and stress\u2013symptom associations is scarce.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>We aimed to identify associations between food intake, psychological distress and gastrointestinal symptoms, and their implications for personalised clinical management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Through the mobile phone application <jats:italic>mySymptoms<\/jats:italic>, 163 users kept, for a median of five weeks, a diary of food intake, psychological distress and gastrointestinal symptoms. We quantified associations between these on the individual level. The presence of individual\u2010level associations was compared over latent classes of daily symptom patterns.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Various gastrointestinal symptoms had demonstrable food\u2013symptom associations (heartburn: 73%, discomfort: 67%, diarrhoea: 57%, bloating: 53%, and gas: 48%). Food\u2013symptom associations for pain in the abdomen (33%) were concentrated in the latent class of individuals with pain in the morning (68%), rather than those with pain in the evening and night (27% and 10%, respectively, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Stress\u2013symptom relations were also found, although only 18% of individuals reported psychological distress.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Personal food\u2013symptom and stress\u2013symptom relations can be detected, and may translate into specific daily symptom patterns. A next step will be to let personal food\u2013symptom and stress\u2013symptom relations serve as the basis for personalised clinical management.<\/jats:p><\/jats:sec>","DOI":"10.1177\/2050640619839859","type":"journal-article","created":{"date-parts":[[2019,3,17]],"date-time":"2019-03-17T05:58:40Z","timestamp":1552802320000},"page":"965-973","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["Relations between food intake, psychological distress, and gastrointestinal symptoms: A diary study"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1931-4926","authenticated-orcid":false,"given":"Egbert","family":"Clevers","sequence":"first","affiliation":[{"name":"Department of Internal Medicine &amp; Clinical Nutrition Institute of Medicine Sahlgrenska Academy University of Gothenburg Gothenburg Sweden"},{"name":"Translational Research Centre for Gastrointestinal Disorders (TARGID) KU Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"T\u00f6rnblom","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine &amp; Clinical Nutrition Institute of Medicine Sahlgrenska Academy University of Gothenburg Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Simr\u00e9n","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine &amp; Clinical Nutrition Institute of Medicine Sahlgrenska Academy University of Gothenburg Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Tack","sequence":"additional","affiliation":[{"name":"Translational Research Centre for Gastrointestinal Disorders (TARGID) KU Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas","family":"Van Oudenhove","sequence":"additional","affiliation":[{"name":"Translational Research Centre for Gastrointestinal Disorders (TARGID) KU Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8]]},"reference":[{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2000.16484"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2018.02.042"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2017.421"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.03.035"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0000000000000411"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2013.105"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1159\/000051878"},{"key":"e_1_2_11_9_2","first-page":"428","article-title":"A prospective study of unexplained visible abdominal bloating","volume":"107","author":"Sullivan SN","year":"1994","journal-title":"N Z Med J"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.03.015"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0000000000000227"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2017-314775"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12689"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.5056\/jnm.2011.17.2.131"},{"key":"e_1_2_11_15_2","unstructured":"ApplicationmySymptoms 2010 https:\/\/skygazerlabs.com\/wp\/(accessed 20 December 2018)."},{"key":"e_1_2_11_16_2","volume-title":"R: A language and environment for statistical computing","author":"R Core Team","year":"2018"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1145\/363958.363994"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.32614\/RJ-2014-011"},{"key":"e_1_2_11_19_2","unstructured":"MassicottePandEddelbuettelD.gtrendsR: Perform and display Google trends queries. 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