{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T17:19:51Z","timestamp":1791047991948,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["UEG Journal"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Spontaneous bacterial peritonitis (SBP) is defined as an ascitic polymorphonuclear cell count (A\u2010PMN)\u2009&gt;\u2009250 cells\/\u00b5l.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aimed to investigate the prognostic value of ascitic fluid cell counts in patients without SBP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>A total of 178 patients were included and stratified by ascitic cell counts at index paracentesis: A\u2010LEUK\u2010low (&lt;250\/\u00b5l), A\u2010LEUK\u2010intermediate (250\u2013500\/\u00b5l) and A\u2010LEUK\u2010SBP (&gt;500\/\u00b5l) for leukocytes; A\u2010PMN\u2010low (&lt;125\/\u00b5l), A\u2010PMN\u2010intermediate (125\u2013250\/\u00b5l) and A\u2010PMN\u2010SBP (&gt;250\/\u00b5l) for PMN cells.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      One\u2010year mortality was comparable between group A\u2010LEUK\u2010SBP (53.9%) and patients with subclinical cell counts (34.5% for A\u2010LEUK\u2010low, 43.5% for A\u2010LEUK\u2010intermediate, log\u2010rank\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.547). However, we observed an increase in one\u2010year mortality already in group A\u2010PMN\u2010intermediate with 75% and A\u2010PMN\u2010SBP with 80.9% (vs 40.5% for A\u2010PMN\u2010low, log\u2010rank\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.016).\n                    <\/jats:p>\n                    <jats:p>\n                      Importantly, increases of A\u2010PMN cell counts between two paracenteses were associated with increased mortality: per 100 cells\/\u00b5l increase of absolute A\u2010PMN cell count: hazard ratio (HR): 1.03 (95% confidence interval (CI): 1.01\u20131.06),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005; per 5% increase of relative PMN cell count: HR: 1.15 (95% CI: 1.06\u20131.26),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patients with PMN cell counts of 125\u2013250\/\u00b5l are at high risk for mortality, which was very similar to SBP patients with PMN cell counts &gt;250\/\u00b5l. This highlights the need for preventive strategies. The prognostic value of changes in relative ascitic PMN cell counts should be evaluated in future studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2050640619843000","type":"journal-article","created":{"date-parts":[[2019,4,6]],"date-time":"2019-04-06T02:48:24Z","timestamp":1554518904000},"page":"651-661","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Ascitic fluid polymorphic nuclear cell count impacts on outcome of cirrhotic patients with ascites"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8181-9146","authenticated-orcid":false,"given":"Benedikt","family":"Simbrunner","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Internal Medicine III Medical University of Vienna Vienna Austria"},{"name":"Vienna Hepatic Hemodynamic Lab Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annika","family":"R\u00f6thenbacher","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Internal Medicine III Medical University of Vienna Vienna Austria"},{"name":"Vienna Hepatic Hemodynamic Lab Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmuth","family":"Haslacher","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Bauer","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Internal Medicine III Medical University of Vienna Vienna Austria"},{"name":"Vienna Hepatic Hemodynamic Lab Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1807-8258","authenticated-orcid":false,"given":"David","family":"Chromy","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Internal Medicine III Medical University of Vienna Vienna Austria"},{"name":"Vienna Hepatic Hemodynamic Lab Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Bucsics","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Internal Medicine III Medical University of Vienna Vienna Austria"},{"name":"Vienna Hepatic Hemodynamic Lab Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Schwabl","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Internal Medicine III Medical University of Vienna Vienna Austria"},{"name":"Vienna Hepatic Hemodynamic Lab Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1813-5769","authenticated-orcid":false,"given":"Rafael","family":"Paternostro","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Internal Medicine III Medical University of Vienna Vienna Austria"},{"name":"Vienna Hepatic Hemodynamic Lab Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Scheiner","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Internal Medicine III Medical University of Vienna Vienna Austria"},{"name":"Vienna Hepatic Hemodynamic Lab Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Trauner","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Internal Medicine III Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2330-0017","authenticated-orcid":false,"given":"Mattias","family":"Mandorfer","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Internal Medicine III Medical University of Vienna Vienna Austria"},{"name":"Vienna Hepatic Hemodynamic Lab Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilse","family":"Schwarzinger","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Reiberger","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Internal Medicine III Medical University of Vienna Vienna Austria"},{"name":"Vienna Hepatic Hemodynamic Lab Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6]]},"reference":[{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60383-9"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2012.12.005"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.13002"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14485"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(00)80422-5"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.05.022"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.05.024"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/liv.12520"},{"key":"e_1_2_10_10_2","doi-asserted-by":"crossref","first-page":"1246-1256.e1","DOI":"10.1053\/j.gastro.2010.06.019","article-title":"Infections in patients with cirrhosis increase mortality four-fold and should be used in determining prognosis","volume":"139","author":"Arvaniti V","year":"2010","journal-title":"Gastroenterology"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2014.01.024"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(05)80280-6"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/liv.12795"},{"key":"e_1_2_10_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(00)80201-9"},{"key":"e_1_2_10_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.05.004"},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.038679"},{"key":"e_1_2_10_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.22395"},{"key":"e_1_2_10_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.07620.x"},{"key":"e_1_2_10_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(97)80250-4"},{"key":"e_1_2_10_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-017-4637-4"},{"key":"e_1_2_10_21_2","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-304038"},{"key":"e_1_2_10_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-013-0337-z"},{"key":"e_1_2_10_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-017-1262-3"},{"key":"e_1_2_10_24_2","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1999.10474144"},{"key":"e_1_2_10_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.03.024"},{"key":"e_1_2_10_26_2","doi-asserted-by":"crossref","first-page":"270456","DOI":"10.1155\/2015\/270456","article-title":"MELD score is not related to spontaneous bacterial peritonitis","volume":"2015","author":"Haddad L","year":"2015","journal-title":"Gastroenterol Res Pract"},{"key":"e_1_2_10_27_2","doi-asserted-by":"publisher","DOI":"10.1177\/2211068212471833"},{"key":"e_1_2_10_28_2","first-page":"32","article-title":"Continuous ambulatory peritoneal dialysis, ascitic and pleural body fluids evaluation with the Mindray BC-6800 hematology analyzer","author":"Fuster O","year":"2018","journal-title":"J Clin Lab Anal"},{"key":"e_1_2_10_29_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.06.065"},{"key":"e_1_2_10_30_2","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14361"},{"key":"e_1_2_10_31_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-015-9688-z"},{"key":"e_1_2_10_32_2","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e3182506dbb"},{"key":"e_1_2_10_33_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28330"},{"key":"e_1_2_10_34_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365521.2017.1411973"},{"key":"e_1_2_10_35_2","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14522"},{"key":"e_1_2_10_36_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-018-3101-1"},{"key":"e_1_2_10_37_2","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13929"},{"key":"e_1_2_10_38_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.08.026"}],"container-title":["United European Gastroenterology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/2050640619843000","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1177\/2050640619843000","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/2050640619843000","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T07:18:43Z","timestamp":1693725523000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1177\/2050640619843000"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1177\/2050640619843000"],"URL":"https:\/\/doi.org\/10.1177\/2050640619843000","archive":["Portico"],"relation":{},"ISSN":["2050-6406","2050-6414"],"issn-type":[{"value":"2050-6406","type":"print"},{"value":"2050-6414","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6]]}}}