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An autoimmune hepatitis diagnosis justifies life\u2010long treatment in most patients in order to prevent development of cirrhosis and end\u2010stage liver disease. The cornerstone of treatment is steroid induction therapy followed by maintenance therapy with azathioprine, which is effective in most cases. For patients who do not respond to standard treatment, second\u2010line treatment with other immunosuppressants can be effective. Treatment should be aimed at biochemical remission of the disease, which is defined as normalization of transaminases and immunoglobulin G. Patients should be monitored intensively during the first months of treatment in order to monitor side\u2010effects, assess symptoms and individualise treatment. Specialist consultation should be sought in difficult\u2010to\u2010treat patients. 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