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Most patients experience a mild course of disease, but one third will develop local complications and\/or organ failure associated with increased morbidity and risk of mortality. Diagnosis of acute pancreatitis is based on typical epigastric pain, elevation of serum lipase or amylase levels, and\/or characteristic findings on imaging. Personalised management is needed in patients with acute pancreatitis. Currently, analgesia, Ringer\u2019s lactate solution\u2010based goal\u2010directed fluid resuscitation and early oral refeeding providing enteral nutrition if not tolerated are the cornerstones for early management. Prophylactic antibiotics or endoscopic retrograde cholangiopancreatography in the absence of cholangitis are considered to be futile. Future clinical trials should address optimal fluid resuscitation, the early administration of anti\u2010inflammatory drugs and the exact role of nutritional support in severe acute pancreatitis. Here, we present a patient case and review the diagnosis, treatment and prognosis of acute pancreatitis.<\/jats:p>","DOI":"10.1177\/2050640620903225","type":"journal-article","created":{"date-parts":[[2020,1,23]],"date-time":"2020-01-23T07:08:28Z","timestamp":1579763308000},"page":"403-409","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":28,"title":["Towards evidence\u2010based and personalised care of acute pancreatitis"],"prefix":"10.1002","volume":"8","author":[{"given":"Guillermo","family":"Garc\u00eda\u2010Rayado","sequence":"first","affiliation":[{"name":"Service of Digestive Diseases University Clinic Hospital Lozano Blesa Arag\u00f3n Health Research Institute (IIS Arag\u00f3n) Zaragoza Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina","family":"C\u00e1rdenas\u2010Ja\u00e9n","sequence":"additional","affiliation":[{"name":"Gastroenterology Department Alicante University General Hospital Alicante Institute for Health and Biomedical Research (ISABIAL) Alicante Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2412-9541","authenticated-orcid":false,"given":"Enrique","family":"de Madaria","sequence":"additional","affiliation":[{"name":"Gastroenterology Department Alicante University General Hospital Alicante Institute for Health and Biomedical Research (ISABIAL) Alicante Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-302779"},{"key":"e_1_2_12_3_1","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1136\/bmj.2.4566.68","article-title":"The blood diastase and lipase changes in acute pancreatitis","volume":"2","author":"Wapshaw H.","year":"1948","journal-title":"BMJ"},{"key":"e_1_2_12_4_1","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD012010.pub2","article-title":"Serum amylase and lipase and urinary trypsinogen and amylase for diagnosis of acute pancreatitis","author":"Rompianesi G","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_12_5_1","doi-asserted-by":"crossref","first-page":"1051e6","DOI":"10.1016\/j.clinbiochem.2012.04.028","article-title":"Rapid urinary trypsinogen\u20102 test in the early diagnosis of acute pancreatitis: a meta\u2010analysis","volume":"45","author":"Chang K","year":"2012","journal-title":"Clin Biochem"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcg.0000436438.60145.5a"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jhbp.515"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2233010680"},{"key":"e_1_2_12_9_1","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.pan.2013.07.063","article-title":"Acute Pancreatitis Guidelines. 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