{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T09:56:34Z","timestamp":1780394194044,"version":"3.54.1"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T00:00:00Z","timestamp":1613433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T00:00:00Z","timestamp":1613433600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["UEG Journal"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and aims<\/jats:title><jats:p>Adenoma detection rate (ADR) in colon cancer screening is most important for cancer prophylaxis. This work is the first three\u2010armed randomised controlled clinical trial aimed at comparing a head\u2010to\u2010head setting standard colonoscopy (SC) with Endocuff\u2010assisted colonoscopy (EC) and cap\u2010assisted colonoscopy (CAC) for improvement of ADR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients from Poland and Germany with independent indication for colonoscopy were randomised into three arms of this trial: EC, CAC and SC. Exclusion criteria were age &lt;18\u00a0years, active Crohn's disease or ulcerative colitis, known stenosis and post\u2010colonic resection status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 585 patients (195 SC, 189 EC and 186 CAC) were enrolled in this study. Indications were not different between the groups (colorectal cancer screening 51%, diagnostic colonoscopy in 31% and post\u2010polypectomy follow\u2010up in 18%; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.94). Withdrawal time was a mean of 7 min in all groups (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.658), and bowel preparation did not differ between the groups. The time to reach the caecum was significantly reduced when using the cap (a mean of 6 min for CAC vs. 7 min for SC; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.0001). There was no significant difference in the primary outcome of the ADR between the groups (EC 32%, CAC 30%, SC 30%; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.815). EC proved to be superior (EC vs. SC) in the sigmoid colon and transverse colon for polyp detection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The use of EC increased the total number of polyps seen during colonoscopy. In contrast to recent studies, no significant improvement of the ADR was detected.<\/jats:p><\/jats:sec>","DOI":"10.1177\/2050640620982952","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T04:45:54Z","timestamp":1608612354000},"page":"443-450","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":20,"title":["Standard versus Endocuff versus cap\u2010assisted colonoscopy for adenoma detection: A randomised controlled clinical trial"],"prefix":"10.1002","volume":"9","author":[{"given":"Martin","family":"Floer","sequence":"first","affiliation":[{"name":"Department of Medicine 1 Klinikum Ibbenbueren Teaching Hospital University of Muenster  M\u00fcnster Germany"},{"name":"Department of Medicine 2 Helios Albert\u2010Schweitzer\u2010Klinik Northeim Teaching Hospital University Goettingen  Northeim 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Hepatology Wroclaw Medical University  Wroclaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elzbieta","family":"Poniewierka","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Wroclaw Medical University  Wroclaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffen","family":"Kunsch","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Gastrointestinal Oncology University Medical Centre Goettingen  Goettingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Detlev","family":"Ameis","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Helios Hospital Helmstedt  Helmstedt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8546-8064","authenticated-orcid":false,"given":"Hauke Sebastian","family":"Heinzow","sequence":"additional","affiliation":[{"name":"Department 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