{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T09:30:59Z","timestamp":1772789459409,"version":"3.50.1"},"reference-count":24,"publisher":"Informa UK Limited","issue":"3","license":[{"start":{"date-parts":[[2025,4,13]],"date-time":"2025-04-13T00:00:00Z","timestamp":1744502400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Post Reprod Health"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Genitourinary syndrome of menopause (GSM) is a common condition, yet there is no accessible, objective clinical method with which to make a diagnosis of vaginal changes associated with GSM. We undertook a feasibility study to assess suitability of different objective diagnostic methods and obtained quantitative scores using a new GSM Assessment Tool (NGAT) and vaginal maturation vlue (VMV). These scores were correlated with patient reported symptoms obtained via a questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>VAginal Health \u2013 What\u2019s Normal (VAN) Study is a prospective, observational, feasibility study, evaluating NGAT and VMV. Sixty women (12 healthy controls and 48 symptomatic) were recruited and had a baseline assessment. The symptomatic women were offered treatment and had a second assessment 16 weeks later.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared with control group, symptomatic women had higher NGAT and VMV scores at baseline. After treatment, in symptomatic women, symptoms improved and NGAT scores reduced, while the median value for VMV was unexpectedly reduced.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This data suggests that clinical assessment and accurate recording of GSM can be supported by an objective scoring system, particularly in primary care and warrants adequately powered future studies to assess the utility of these methods in clinical and research setting.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20533691251332321","type":"journal-article","created":{"date-parts":[[2025,4,13]],"date-time":"2025-04-13T03:26:02Z","timestamp":1744514762000},"page":"163-172","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility of developing a new tool for assessing vaginal health in women with Genitourinary Syndrome of Menopause; The VAN study"],"prefix":"10.1080","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0468-9151","authenticated-orcid":false,"given":"Paula","family":"Briggs","sequence":"first","affiliation":[{"name":"Liverpool Women\u2019s NHS Foundation Trust, Liverpool, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Evans","sequence":"additional","affiliation":[{"name":"Manchester University NHS Foundation Trust, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Lane","sequence":"additional","affiliation":[{"name":"Department of Women\u2019s and Children\u2019s Health, Centre for Women\u2019s Health Research, University of Liverpool, Liverpool, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lora","family":"Kiosseva","sequence":"additional","affiliation":[{"name":"Yourdaye, Sofia, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo","family":"Drury","sequence":"additional","affiliation":[{"name":"Department of Women\u2019s and Children\u2019s Health, University of Liverpool, Liverpool, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2097-609X","authenticated-orcid":false,"given":"Tim","family":"Hillard","sequence":"additional","affiliation":[{"name":"University Hospitals Dorset, Poole, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick","family":"Panay","sequence":"additional","affiliation":[{"name":"Queen Charlotte\u2019s and Chelsea Hospital, London, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dharani K","family":"Hapangama","sequence":"additional","affiliation":[{"name":"Department of Women\u2019s and Children\u2019s Health, Centre for Women\u2019s Health Research, University of Liverpool, Liverpool, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,4,13]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000000329"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/13697137.2019.1600499"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.3109\/13697137.2015.1107039"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/20533691211065808"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000001609"},{"key":"e_1_3_5_7_2","unstructured":"National Institute for Health and Care Excellence. Clinical guidelines. In: Menopause: identification and management. London: National Institute for Health and Care Excellence (NICE)."},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5122(94)00863-3"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000001788"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000001496"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000001406"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/20533691231199803"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/20533691221135906"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000000281"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/20533691241246366"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000002369"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsxm.2019.10.010"},{"key":"e_1_3_5_18_2","first-page":"261","volume-title":"Advances in understanding and management. Pre-Menopause, menopause and beyond","author":"Panay N GSM\/VVA","year":"2017","unstructured":"Panay N GSM\/VVA. Advances in understanding and management. Pre-Menopause, menopause and beyond. New York City: Springer International Publishing, 2017, pp. 261\u2013268."},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1177\/2053369121997673"},{"key":"e_1_3_5_20_2","unstructured":"Gavrilova N Dude A Hoffman JN et al. Vaginal cytological characteristics as a biomeasure of estrogenization in a community-based population of older women. In: The national social life health & aging project. Chicago: University of Chicago."},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.11613\/BM.2015.015"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000001570"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0320(19990301)35:3<196::AID-CYTO2>3.0.CO;2-V"},{"key":"e_1_3_5_24_2","first-page":"249","article-title":"The maturation value","volume":"11","author":"Meisels A","year":"1967","unstructured":"Meisels A. The maturation value. Acta Cytol 1967; 11: 249\u2013255.","journal-title":"Acta Cytol"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2019.03.013"}],"container-title":["Post Reproductive Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20533691251332321","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/20533691251332321","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20533691251332321","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T19:26:03Z","timestamp":1766517963000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/20533691251332321"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,13]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1177\/20533691251332321"],"URL":"https:\/\/doi.org\/10.1177\/20533691251332321","relation":{},"ISSN":["2053-3691","2053-3705"],"issn-type":[{"value":"2053-3691","type":"print"},{"value":"2053-3705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,13]]}}}