{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T16:19:06Z","timestamp":1792685946072,"version":"4.5.0"},"reference-count":18,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Can J Kidney Health Dis"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title>Rationale:<\/jats:title>\n                    <jats:p>Acute focal bacterial nephritis (AFBN) has mainly been reported in pediatrics. It may be an underdiagnosed condition in adults because it resembles acute pyelonephritis (APN) in its clinical presentation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presenting concerns of the patients:<\/jats:title>\n                    <jats:p>Two young women (25 and 27 years old, respectively) presented with complaints compatible with a diagnosis of APN. However in both, fever was of high grade, persistent for several days in spite of antibiotic administration, and there was demonstrated worsening of the inflammatory biomarkers. A contrast-enhanced computed tomography (CECT) led to the diagnosis in both cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Diagnoses:<\/jats:title>\n                    <jats:p>Contrast-enhanced computed tomography reveals the most sensitive and specific images of AFBN. This includes wedge-shaped lesions with decreased enhancement, which may be focal or multifocal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions (including prevention and lifestyle):<\/jats:title>\n                    <jats:p>Antibiotic therapy for at least 3 weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcomes:<\/jats:title>\n                    <jats:p>Resolution of AFBN was obtained after 3 weeks of antibiotics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Lessons learned:<\/jats:title>\n                    <jats:p>Our 2 cases illustrate the importance of CECT imaging to confirm the diagnosis of AFBN. Interstitial bacterial inflammation may have a worse prognosis if not diagnosed early and efficiently treated. Unlike APN, the management of AFBN requires at least 3 weeks of antibiotics to prevent the development of renal scarring and renal abscess.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2054358119884310","type":"journal-article","created":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T03:24:38Z","timestamp":1571973878000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Acute Focal Bacterial Nephritis: Two Cases and Review of the Literature"],"prefix":"10.1177","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4026-4268","authenticated-orcid":false,"given":"Adnane","family":"Guella","sequence":"first","affiliation":[{"name":"University Hospital Sharjah, United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arshee","family":"Khan","sequence":"additional","affiliation":[{"name":"University Hospital Sharjah, United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dima","family":"Jarrah","sequence":"additional","affiliation":[{"name":"University Hospital Sharjah, United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,10,25]]},"reference":[{"key":"bibr1-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1148\/132.3.553"},{"key":"bibr2-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2009.07.010"},{"key":"bibr3-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-5347(17)49216-0"},{"key":"bibr4-2054358119884310","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1542\/peds.87.5.728","volume":"87","author":"Rathore MH","year":"1991","journal-title":"Pediatrics"},{"key":"bibr5-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1159\/000441955"},{"key":"bibr6-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-017-2336-6"},{"key":"bibr7-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-004-1646-2"},{"key":"bibr8-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181d8631a"},{"key":"bibr9-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2013.08.097"},{"key":"bibr10-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2016.12.002"},{"key":"bibr11-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-007-0589-9"},{"key":"bibr12-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedneo.2014.08.002"},{"key":"bibr13-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(88)80172-0"},{"key":"bibr14-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1016\/S1684-1182(10)60033-3"},{"key":"bibr15-2054358119884310","first-page":"257","volume":"137","author":"Siegel MJ","year":"1981","journal-title":"Am J Radiol"},{"key":"bibr16-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1136\/adc.60.5.475"},{"key":"bibr17-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31818ffe7d"},{"key":"bibr18-2054358119884310","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-0917"}],"container-title":["Canadian Journal of Kidney Health and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2054358119884310","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2054358119884310","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2054358119884310","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:23:13Z","timestamp":1777389793000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2054358119884310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":18,"alternative-id":["10.1177\/2054358119884310"],"URL":"https:\/\/doi.org\/10.1177\/2054358119884310","relation":{},"ISSN":["2054-3581","2054-3581"],"issn-type":[{"value":"2054-3581","type":"print"},{"value":"2054-3581","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1]]},"article-number":"2054358119884310"}}