{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T02:15:37Z","timestamp":1777601737593,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Can J Kidney Health Dis"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Rationale:<\/jats:title>\n                    <jats:p>Nocturnal enuresis is a common symptom of nephrogenic diabetes insipidus (NDI) in children. Published reports on the treatment of nocturnal enuresis in this population are scarce. Presenting concern of the patient: 2 brothers, aged 8 and 9 years, presented for outpatient pediatric nephrology follow-up. Despite being medically stable on their current medication regimen, they both experienced significant distress due to primary nocturnal enuresis, including decreased self-esteem and social stress.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Diagnoses:<\/jats:title>\n                    <jats:p>The brothers had primary nocturnal enuresis related to their high urine output from NDI. Interventions: we describe a case of 2 brothers with NDI in whom indomethacin was added to their pharmacologic treatment specifically to address enuresis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome:<\/jats:title>\n                    <jats:p>Both brothers experienced a significant decrease in the frequency of nocturnal enuresis and improvement in their perceived quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Teaching points:<\/jats:title>\n                    <jats:p>Nocturnal enuresis is a bothersome symptom of NDI with adverse psychological effects. Indomethacin can improve nocturnal enuresis in some patients. Treatment with nonsteroidal anti-inflammatory drugs carries a risk of gastrointestinal and kidney side effects. We advocate for a patient-centered approach to the treatment of NDI which includes optimizing both the medical and the psychological needs of the patient.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20543581221114693","type":"journal-article","created":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T06:18:07Z","timestamp":1658816287000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["The Use of Indomethacin for Nocturnal Enuresis in Children With Nephrogenic Diabetes Insipidus: A Case Report and Review of the Literature"],"prefix":"10.1177","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4685-0612","authenticated-orcid":false,"given":"Erin","family":"Hedin","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Nephrology, University of Alberta, Edmonton, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2312-7541","authenticated-orcid":false,"given":"Abdullah","family":"Alabbas","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Nephrology, University of Alberta, Edmonton, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,7,26]]},"reference":[{"key":"bibr1-20543581221114693","doi-asserted-by":"publisher","DOI":"10.5414\/CN109127"},{"key":"bibr2-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1177\/003591576505801202"},{"key":"bibr3-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-012-2118-8"},{"key":"bibr4-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1042\/cs0660709"},{"key":"bibr5-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfy027"},{"key":"bibr6-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2012.02577.x"},{"key":"bibr7-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1542\/peds.105.S3.935"},{"key":"bibr8-20543581221114693","doi-asserted-by":"publisher","DOI":"10.4137\/CMPed.S13068"},{"key":"bibr9-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2006.04.004"},{"key":"bibr10-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38232.680567.EB"},{"key":"bibr11-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1590\/2175-8239-jbn-2018-0107"},{"key":"bibr12-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1981.tb07170.x"},{"key":"bibr13-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1136\/adc.81.1.57"},{"issue":"7","key":"bibr14-20543581221114693","first-page":"2291","volume":"3","author":"H\u00f6rl WH.","year":"2010","journal-title":"Pharm Basel Switz"},{"issue":"5","key":"bibr15-20543581221114693","first-page":"985","volume":"33","author":"Reiff A","year":"2006","journal-title":"J Rheumatol"},{"key":"bibr16-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-005-2057-8"},{"key":"bibr17-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.10.1247"},{"key":"bibr18-20543581221114693","doi-asserted-by":"publisher","DOI":"10.2174\/1381612053764922"},{"key":"bibr19-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1001\/jama.296.13.jrv60015"},{"key":"bibr20-20543581221114693","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2015.03.008."}],"container-title":["Canadian Journal of Kidney Health and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20543581221114693","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/20543581221114693","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20543581221114693","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:24:21Z","timestamp":1777389861000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/20543581221114693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":20,"alternative-id":["10.1177\/20543581221114693"],"URL":"https:\/\/doi.org\/10.1177\/20543581221114693","relation":{},"ISSN":["2054-3581","2054-3581"],"issn-type":[{"value":"2054-3581","type":"print"},{"value":"2054-3581","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"article-number":"20543581221114693"}}