{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:58:30Z","timestamp":1777503510147,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T00:00:00Z","timestamp":1743379200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T00:00:00Z","timestamp":1743379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Can J Kidney Health Dis"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Tracking the evaluation process of living kidney donor candidates facilitates benchmarking and can inform process redesign to improve experiences with the evaluation and enable more living donor kidney transplantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We reviewed the medical records for all living donor candidates who were actively undergoing evaluation at any time between January 1, 2013, and December 31, 2016, at the London Health Sciences Centre in London, Ontario, Canada. We abstracted information on demographic factors, the evaluation process, reasons for a delayed evaluation, reasons for an evaluation termination (eg, donation, decline, withdrawal, loss to follow-up), frequency and timing of evaluation testing, and recipient dialysis status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Over time, the number of living donor kidney transplants increased from 22 in 2013 to 32 in 2016 (18% and 34% of which were pre-emptive, respectively). The median number of candidates coming forward doubled from 167 in 2013 (2 candidates per recipient) to 348 in 2016 (4 candidates per recipient). Median time from first contact until donation decreased from 12.8 months in 2013 to 7.1 months in 2016 (a 45% reduction). The time from computed tomography (CT) angiography until donation (n = 74) was a median of 75 (interquartile range [IQR] = 36, 180) days, the longest single step in the evaluation. Common reasons for delay included waiting for the referral of their intended recipient for transplant evaluation (11% of candidates) and a need for the donor candidate to lose weight (8% of candidates). Donors completed the main evaluation tests on a median of 5 different dates. Thirty-six recipients started dialysis after their living donor candidates\u2019 evaluation had been underway for at least 3 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Tracking the steps and reasons for an inefficient living kidney donor evaluation process can be used for quality improvement, and efficiency improvements are expected to translate into improved outcomes and experiences.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20543581251323964","type":"journal-article","created":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T00:29:08Z","timestamp":1744158548000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The Flow of Living Kidney Donor Candidates Through the Evaluation Process: A Single-Center Experience in Ontario, Canada"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9650-9105","authenticated-orcid":false,"given":"Steven","family":"Habbous","sequence":"first","affiliation":[{"name":"Department of Epidemiology &amp; Biostatistics, Western University, London, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beth","family":"Montesi","sequence":"additional","affiliation":[{"name":"Multi-Organ Transplant Program, University Hospital, London, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christy","family":"Masse","sequence":"additional","affiliation":[{"name":"Multi-Organ Transplant Program, University Hospital, London, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corinne","family":"Weernink","sequence":"additional","affiliation":[{"name":"Multi-Organ Transplant Program, University Hospital, London, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sisira","family":"Sarma","sequence":"additional","affiliation":[{"name":"Department of Epidemiology &amp; Biostatistics, Western University, London, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet A.","family":"Begen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology &amp; Biostatistics, Western University, London, ON, Canada"},{"name":"Ivey School of Business, Western University, London, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0129-7091","authenticated-orcid":false,"given":"Ngan N.","family":"Lam","sequence":"additional","affiliation":[{"name":"Divisions of Transplant Medicine and Nephrology, Cumming School of Medicine, University of Calgary, AB, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Dipchand","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Dalhousie University, Halifax, NS Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0404-7319","authenticated-orcid":false,"given":"Seychelle","family":"Yohanna","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3466-6305","authenticated-orcid":false,"given":"Dervla M.","family":"Connaughton","sequence":"additional","affiliation":[{"name":"Department of Epidemiology &amp; Biostatistics, Western University, London, ON, Canada"},{"name":"Multi-Organ Transplant Program, University Hospital, London, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2403-2392","authenticated-orcid":false,"given":"Lianne","family":"Barnieh","sequence":"additional","affiliation":[{"name":"Department of Epidemiology &amp; Biostatistics, Western University, London, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3398-3114","authenticated-orcid":false,"given":"Amit X.","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Epidemiology &amp; Biostatistics, Western University, London, ON, Canada"},{"name":"Division of Nephrology, Department of Medicine, Western University, London, ON, Canada"},{"name":"ICES, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,3,31]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40472-018-0184-y"},{"issue":"10","key":"e_1_3_2_3_2","article-title":"Kidney paired donation protocol for participating donors 2014","volume":"99","author":"Richardson R","year":"2015","unstructured":"Richardson R, Connelly M, Dipchand C, et al. Kidney paired donation protocol for participating donors 2014. Transplantation. 2015;99(10 suppl 1):S1-S88.","journal-title":"Transplantation"},{"issue":"8","key":"e_1_3_2_4_2","doi-asserted-by":"crossref","DOI":"10.1097\/TP.0000000000001770","article-title":"KDIGO clinical practice guideline on the evaluation and care of living kidney donors","volume":"101","author":"Lentine KL","year":"2017","unstructured":"Lentine KL, Kasiske BL, Levey AS, et al. KDIGO clinical practice guideline on the evaluation and care of living kidney donors. Transplantation. 2017;101(8 suppl 1):S7-S105.","journal-title":"Transplantation"},{"issue":"5","key":"e_1_3_2_5_2","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1053\/j.ajkd.2017.10.018","article-title":"Evaluation of kidney donors: core curriculum 2018","volume":"71","author":"Sawinski D","year":"2018","unstructured":"Sawinski D, Locke JE. Evaluation of kidney donors: core curriculum 2018. 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Transplantation. 2018;102(7):e345-e353.","journal-title":"Transplantation"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14732"},{"key":"e_1_3_2_9_2","article-title":"The experiences and impact of being deemed ineligible for living kidney donation: semi-structured interview study","author":"Ralph AF","year":"2019","unstructured":"Ralph AF, Chadban SJ, Butow P, et al. The experiences and impact of being deemed ineligible for living kidney donation: semi-structured interview study. 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Accessed March 16 2025. https:\/\/odt.nhs.uk\/odt-structures-and-standards\/key-strategies\/archived-strategies\/living-donor-transplantation-strategy-2020\/"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-010-1855-y"}],"container-title":["Canadian Journal of Kidney Health and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20543581251323964","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/20543581251323964","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20543581251323964","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:21:53Z","timestamp":1777389713000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/20543581251323964"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,31]]},"references-count":16,"alternative-id":["10.1177\/20543581251323964"],"URL":"https:\/\/doi.org\/10.1177\/20543581251323964","relation":{},"ISSN":["2054-3581","2054-3581"],"issn-type":[{"value":"2054-3581","type":"print"},{"value":"2054-3581","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,31]]},"article-number":"20543581251323964"}}