{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:29:56Z","timestamp":1777858196887,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery Open Reports"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>A 10-year-old spayed female American Shorthair cat underwent renal transplantation due to worsening chronic kidney disease secondary to polycystic kidney disease. During transplantation, the right kidney grossly appeared to be more diseased than the left and was firmly adhered to the surrounding tissues. An intraoperative fine-needle aspirate of the right native kidney revealed inflammatory cells but no evidence of neoplasia. To create space for the allograft, a right nephrectomy was performed. Following nephrectomy, the right native kidney was submitted for biopsy. Biopsy results revealed a renal cell carcinoma. Although the cat initially recovered well from surgery, delayed graft function was a concern in the early postoperative period. Significant azotemia persisted and the cat began to have diarrhea. Erythematous skin lesions developed in the perineal and inguinal regions, which were suspected to be secondary to thromboembolic disease based on histopathology. The cat\u2019s clinical status continued to decline with development of signs of sepsis, followed by marked obtundation with uncontrollable seizures. Given the postoperative diagnosis of renal cell carcinoma and the cat\u2019s progressively declining clinical status, humane euthanasia was elected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Relevance and novel information<\/jats:title>\n                    <jats:p>This case is the first to document renal cell carcinoma in a cat with polycystic kidney disease. An association of the two diseases has been reported in the human literature, but such a link has yet to be described in veterinary medicine. Given the association reported in the human literature, a plausible relationship between polycystic kidney disease and renal cell carcinoma in cats merits further investigation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2055116918766152","type":"journal-article","created":{"date-parts":[[2018,5,4]],"date-time":"2018-05-04T03:16:07Z","timestamp":1525403767000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Renal cell carcinoma in a cat with polycystic kidney disease undergoing renal transplantation"],"prefix":"10.1177","volume":"4","author":[{"given":"Daniel J","family":"Adams","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jolie A","family":"Demchur","sequence":"additional","affiliation":[{"name":"Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lillian R","family":"Aronson","sequence":"additional","affiliation":[{"name":"Section of Surgery, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,5,4]]},"reference":[{"key":"bibr1-2055116918766152","first-page":"2025","volume-title":"Veterinary surgery: small animal","author":"Aronson LR","year":"2012"},{"key":"bibr2-2055116918766152","doi-asserted-by":"publisher","DOI":"10.2460\/javma.248.3.275"},{"key":"bibr3-2055116918766152","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000141776.38527.BB"},{"key":"bibr4-2055116918766152","first-page":"618","volume-title":"Pathologic basis of veterinary disease","author":"Zachary JF","year":"2012","edition":"5"},{"key":"bibr5-2055116918766152","doi-asserted-by":"publisher","DOI":"10.1016\/S1098-612X(03)00052-4"},{"key":"bibr6-2055116918766152","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra022161"},{"key":"bibr7-2055116918766152","doi-asserted-by":"publisher","DOI":"10.4236\/oju.2015.56013"},{"key":"bibr8-2055116918766152","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00406.2014"},{"key":"bibr9-2055116918766152","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2009.02.078"},{"key":"bibr10-2055116918766152","first-page":"1145","volume-title":"Textbook of veterinary internal medicine","author":"Fox PR","year":"2007","edition":"6"},{"key":"bibr11-2055116918766152","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.15-0697"},{"key":"bibr12-2055116918766152","doi-asserted-by":"publisher","DOI":"10.1016\/S1098-612X(99)90205-X"},{"key":"bibr13-2055116918766152","doi-asserted-by":"publisher","DOI":"10.1177\/030098589403100611"},{"key":"bibr14-2055116918766152","first-page":"21","volume":"5","author":"Engle GC","year":"1969","journal-title":"J Am Anim Hosp Assoc"},{"key":"bibr15-2055116918766152","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318299f12e"},{"key":"bibr16-2055116918766152","first-page":"473","volume":"94","author":"Migaki G.","year":"1982","journal-title":"Prog Clin Biol Res"}],"container-title":["Journal of Feline Medicine and Surgery Open Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2055116918766152","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2055116918766152","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2055116918766152","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:09:24Z","timestamp":1777507764000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2055116918766152"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1177\/2055116918766152"],"URL":"https:\/\/doi.org\/10.1177\/2055116918766152","relation":{},"ISSN":["2055-1169","2055-1169"],"issn-type":[{"value":"2055-1169","type":"print"},{"value":"2055-1169","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1]]},"article-number":"2055116918766152"}}