{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T22:41:15Z","timestamp":1779921675743,"version":"3.53.1"},"reference-count":58,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery Open Reports"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>A 2-year-old polytraumatized male cat was admitted to a teaching hospital for correction of a defective inguinal herniorrhaphy. Upon arrival, the cat showed signs of neuropathic pain, including allodynia and hyperalgesia. Analgesic therapy was initiated with methadone and metamizole; however, 24 h later, the signs of pain continued. Reparative surgery was performed, and a multimodal analgesic regimen was administered (methadone, ketamine, wound catheter and epidural anesthesia). Postoperatively, the cat showed signs of severe pain, assessed using the UNESP-Botucatu multidimensional composite pain scale. Rescue analgesia was initiated, which included methadone, bupivacaine (subcutaneous wound-diffusion catheter) and transversus abdominis plane block. Because the response was incomplete, co-adjuvant therapy (pregabalin and electroacupuncture) was then implemented. Fourteen days after admission, the patient was discharged with oral tramadol and pregabalin for at-home treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Relevance and novel information<\/jats:title>\n                    <jats:p>Neuropathic pain is caused by a primary lesion or dysfunction in the nervous system and is a well-described complication following trauma, surgical procedures such as hernia repair, and inadequate analgesia. The aims of this report are to: (1) describe a presentation of neuropathic pain to highlight the recognition of clinical signs such as allodynia and hyperalgesia in cats; and (2) describe treatment of multi-origin, severe, long-standing, \u2018mixed\u2019 pain (acute inflammatory with a neuropathic component). The patient was managed using multiple analgesic strategies (multimodal analgesia), including opioids, non-steroidal anti-inflammatory drugs, locoregional anesthesia, co-adjuvant drugs and non-pharmacological therapy (electroacupuncture).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2055116919855809","type":"journal-article","created":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T06:25:06Z","timestamp":1560839106000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Multimodal analgesia for treatment of allodynia and hyperalgesia after major trauma in a cat"],"prefix":"10.1177","volume":"5","author":[{"given":"Mariela","family":"Goich","sequence":"first","affiliation":[{"name":"Escuela de Medicina Veterinaria, Facultad de Ciencias de la vida, Universidad Andres Bello"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandra","family":"Bascu\u00f1\u00e1n","sequence":"additional","affiliation":[{"name":"University of Chile, Veterinary Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricio","family":"Fa\u00fandez","sequence":"additional","affiliation":[{"name":"University of Chile, Veterinary Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Vald\u00e9s","sequence":"additional","affiliation":[{"name":"University of Chile, Veterinary Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,6,18]]},"reference":[{"key":"bibr1-2055116919855809","doi-asserted-by":"publisher","DOI":"10.4067\/S0301-732X2014000300020"},{"key":"bibr2-2055116919855809","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2016.00012"},{"key":"bibr3-2055116919855809","unstructured":"Merskey H, Bogduk N. Pain terms, a current list with definitions and notes on usage, classification of chronic pain. 2nd ed. Seattle, WA: IASP Press, 1994."},{"key":"bibr4-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2008.09.001"},{"key":"bibr5-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2009.04.001"},{"key":"bibr6-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000002238"},{"key":"bibr7-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2007.00293.x"},{"key":"bibr8-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1503\/cjs.008314"},{"key":"bibr9-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2006.tb12233.x"},{"key":"bibr10-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)01307-0"},{"key":"bibr11-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2008.06.008"},{"key":"bibr12-2055116919855809","doi-asserted-by":"publisher","DOI":"10.2478\/pjvs-2014-0030"},{"key":"bibr13-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1111\/jvp.12471"},{"key":"bibr14-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X15572970"},{"key":"bibr15-2055116919855809","doi-asserted-by":"crossref","unstructured":"Hammond R, Macdonald C, Nicholson A. Opioid analgesics. In: Maddison JE, Page SW, Church DB (eds). Small animal clinical pharmacology. 2nd ed. Edinburgh: WB Saunders, 2008, pp 309\u2013329.","DOI":"10.1016\/B978-070202858-8.50016-6"},{"key":"bibr16-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2015.04.007"},{"key":"bibr17-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2012.00736.x"},{"key":"bibr18-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X14558893"},{"key":"bibr19-2055116919855809","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.75.8.716"},{"key":"bibr20-2055116919855809","doi-asserted-by":"crossref","unstructured":"Epstein ME. Opioids. In: Gaynor JS, Muir W (eds). Handbook of veterinary pain management. 3rd ed. St Louis, MO: Elsevier Mosby, 2015, pp 161\u2013195.","DOI":"10.1016\/B978-0-323-08935-7.00009-0"},{"key":"bibr21-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijoa.2013.04.013"},{"key":"bibr22-2055116919855809","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2002.221.666"},{"key":"bibr23-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.10-0565"},{"key":"bibr24-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1002\/9781119421375.ch15"},{"key":"bibr25-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(99)00044-5"},{"key":"bibr26-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-08935-7.00014-4"},{"key":"bibr27-2055116919855809","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2002.221.72"},{"key":"bibr28-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1111\/vaa.12057"},{"key":"bibr29-2055116919855809","first-page":"230","volume":"40","author":"Bermudez E.","year":"2011","journal-title":"Revista Chilena de Anestesia"},{"key":"bibr30-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3181e30b9f"},{"key":"bibr31-2055116919855809","unstructured":"Portela DA, Fuensalida SE, Otero PE. Bloqueo de los nervios de la pared abdominal en el plano del m\u00fasculo transverso abdominal. In: Otero PE, Portela DA (eds). Manual de anestesia regional en animales de compa\u00f1\u00eda: anatom\u00eda para bloqueos guiados por ecograf\u00eda y neuroestimulaci\u00f3n. Buenos Aires: Editorial Intermedica, 2017, pp 248\u2013254."},{"key":"bibr32-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000000101"},{"key":"bibr33-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1590\/S0103-84782009000900047"},{"key":"bibr34-2055116919855809","first-page":"653270","volume":"2015","author":"Marques VI","journal-title":"Evid Based Complement Alternat Med"},{"key":"bibr35-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2006.00322.x"},{"key":"bibr36-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2008.00717.x"},{"key":"bibr37-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e31822a24c2"},{"key":"bibr38-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/j.jor.2017.03.012"},{"key":"bibr39-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2010.05.004"},{"key":"bibr40-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X12454418"},{"key":"bibr41-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2007.10.007"},{"key":"bibr42-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2011.06.008"},{"key":"bibr43-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1998.00651.x"},{"key":"bibr44-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2009.00487.x"},{"key":"bibr45-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1053\/j.tcam.2009.10.001"},{"key":"bibr46-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2008.06.002"},{"key":"bibr47-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X13476033"},{"key":"bibr48-2055116919855809","doi-asserted-by":"publisher","DOI":"10.2460\/javma.236.7.751"},{"key":"bibr49-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2012.00769.x"},{"key":"bibr50-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.14-0602"},{"key":"bibr51-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X17730173"},{"key":"bibr52-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X12470828"},{"key":"bibr53-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2013.04.007"},{"key":"bibr54-2055116919855809","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2018.00136"},{"key":"bibr55-2055116919855809","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.70.12.1465"},{"key":"bibr56-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-014-0252-1"},{"key":"bibr57-2055116919855809","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2010.07.015"},{"key":"bibr58-2055116919855809","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1365-2885.2007.00921.x","volume":"31","author":"Pypendop BH","year":"2008","journal-title":"J Vet Pharmacol Ther"}],"container-title":["Journal of Feline Medicine and Surgery Open Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2055116919855809","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2055116919855809","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2055116919855809","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:09:49Z","timestamp":1777507789000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2055116919855809"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":58,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1177\/2055116919855809"],"URL":"https:\/\/doi.org\/10.1177\/2055116919855809","relation":{},"ISSN":["2055-1169","2055-1169"],"issn-type":[{"value":"2055-1169","type":"print"},{"value":"2055-1169","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1]]},"article-number":"2055116919855809"}}