{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:30:51Z","timestamp":1777858251295,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery Open Reports"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>A 13-year-old neutered female domestic shorthair rescue cat presented asymptomatically with raised hepatic enzymes following a routine pre-anaesthetic blood test. Cholangitis was suspected, and supportive treatment with 2 weeks of amoxicillin\u2013clavulanic acid and 4 weeks of ursodeoxycholic acid and S-adenosylmethionine was trialled, with no improvement in biochemistry parameters. Clinicopathological investigations also revealed a markedly raised total bilirubin and abnormal bile acid stimulation test. Abdominal ultrasonography revealed pathological changes in the gallbladder, hepatomegaly with increased echogenicity and markedly thickened common bile duct walls. An exploratory laparotomy was performed revealing a grossly abnormal gallbladder with a small rupture at the dorsal fundus, which was managed via cholecystectomy. Pancreatic and hepatic biopsies were collected concurrently. Histopathology from the submitted samples revealed a gallbladder adenoma, chronic neutrophilic cholangitis and nodular hyperplasia of the pancreas. Culture of the gallbladder bile was negative but may be attributable to the initial treatment with antibiosis. At the time of writing, 5 months postoperatively, the cat had recovered well and remained asymptomatic and clinically healthy, but hepatic enzymes and bilirubin were only mildly reduced from the preoperative levels, despite the cat remaining clinically normal. Relevance and novel information To our knowledge, this is the first case of a gallbladder adenoma confirmed histopathologically in a feline patient. Our findings suggest that although gallbladder neoplasia is rare in cats, this benign tumour should be considered a differential diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2055116921997665","type":"journal-article","created":{"date-parts":[[2021,3,15]],"date-time":"2021-03-15T10:36:57Z","timestamp":1615804617000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Gallbladder adenoma in a domestic shorthair cat"],"prefix":"10.1177","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2089-9215","authenticated-orcid":false,"given":"Catherine","family":"Broadbridge","sequence":"first","affiliation":[{"name":"Lumbry Park Veterinary Specialists, Alton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samantha S","family":"Taylor","sequence":"additional","affiliation":[{"name":"Lumbry Park Veterinary Specialists, Alton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen","family":"Renfrew","sequence":"additional","affiliation":[{"name":"Lumbry Park Veterinary Specialists, Alton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Gemignani","sequence":"additional","affiliation":[{"name":"Lumbry Park Veterinary Specialists, Alton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veronique","family":"Livet","sequence":"additional","affiliation":[{"name":"Lumbry Park Veterinary Specialists, Alton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"Vicek","sequence":"additional","affiliation":[{"name":"Finn Pathologists, Harleston, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie","family":"Dobromylskyj","sequence":"additional","affiliation":[{"name":"Finn Pathologists, Harleston, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,3,14]]},"reference":[{"key":"bibr1-2055116921997665","doi-asserted-by":"crossref","unstructured":"Meuten DJ. Tumors in domestic animals. 5th ed. 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Cancer of the gastrointestinal tract: hepatobiliary tumors. In: Withrow SJ, Vail DM, Page RL (eds). Withrow & MacEwen\u2019s small animal clinical oncology. 5th ed. St Louis, MO: Elsevier, 2013, pp 405\u2013411."},{"key":"bibr11-2055116921997665","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1994.tb00496.x"},{"key":"bibr12-2055116921997665","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12280"},{"key":"bibr13-2055116921997665","doi-asserted-by":"publisher","DOI":"10.1177\/030098589603300506"},{"key":"bibr14-2055116921997665","unstructured":"Rothuizen J, Bunch SE, Charles JE, et al. WSAVA standards for clinical and histological diagnosis of canine and feline liver diseases. 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