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This systematic review aims to synthesize the literature assessing CH technology's impact on psychological wellbeing and\/or QoL of people with MS (PwMS) and\/or their caregivers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This systematic review's protocol is registered with International Prospective Register of Systematic Reviews (PROSPERO) with identification number CRD42023402434. CINAHL, Web of Science, PubMed, Embase, and PsycINFO databases were searched with terms relating to (a) CH; (b) MS; (c) psychological wellbeing\/QoL; and (d) caregivers\/people with MS. Of 2821 screened articles, 47 met the eligibility criteria, with just three including MS caregivers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Heterogenous interventions supporting self-management (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200920 studies), education (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200917 studies), psychological (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200914 studies) or physical (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u20099 studies) rehabilitation and peer support (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u20095 studies) were found. CH technologies had mixed effectiveness in improving psychological and QoL outcomes, with results potentially impacted by technology type, intervention and target group. The study's findings have limited generalizability to improve access across sub-national locations, with no studies disaggregating between urban and rural residence and the majority conducted in the USA and Western Europe.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CH technologies show promise in improving psychological wellbeing and QoL among PwMS and their caregivers. However, this necessitates further study comparing connected health and MS subtypes to improve reproducibility and effectiveness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20552076251326230","type":"journal-article","created":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T08:03:32Z","timestamp":1743494612000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Impact of connected health on the psychological wellbeing and quality of life of people with multiple sclerosis and their caregivers: A systematic review"],"prefix":"10.1177","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1523-3950","authenticated-orcid":false,"given":"Joan","family":"Alaboson","sequence":"first","affiliation":[{"name":"Maynooth University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5946-377X","authenticated-orcid":false,"given":"Laura","family":"Coffey","sequence":"additional","affiliation":[{"name":"Maynooth University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5275-685X","authenticated-orcid":false,"given":"Sowmya","family":"Shrivastava","sequence":"additional","affiliation":[{"name":"Maynooth University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9464-3956","authenticated-orcid":false,"given":"Adeola","family":"Ade-Alao","sequence":"additional","affiliation":[{"name":"Department of Biology, Federal University of Technology, Akure"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0368-4626","authenticated-orcid":false,"given":"Rebecca","family":"Maguire","sequence":"additional","affiliation":[{"name":"Maynooth University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,3,31]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/09638280310001608591"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.7224\/1537-2073.2016-016"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1039\/9781788016070-00001"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-041249"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-021-03041-7"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2020.07.073"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2016.11.067"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/hsc.13687"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.7224\/1537-2073.2012-030"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/08870446.2016.1139112"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458517694432"},{"key":"e_1_3_3_13_2","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1080\/09638280701707324","article-title":"A descriptive profile of caregivers of older adults with MS and the assistance they provide","volume":"30","author":"Finlayson M","year":"2008","unstructured":"Finlayson M, Cho C. 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