{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T08:09:05Z","timestamp":1779091745810,"version":"3.51.4"},"reference-count":52,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","award":["RS-2022-KH129545"],"award-info":[{"award-number":["RS-2022-KH129545"]}],"id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","award":["RS-2025-02215487"],"award-info":[{"award-number":["RS-2025-02215487"]}],"id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003662","name":"Korea Evaluation Institute of Industrial Technology","doi-asserted-by":"publisher","award":["RS-2025-02306270"],"award-info":[{"award-number":["RS-2025-02306270"]}],"id":[{"id":"10.13039\/501100003662","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT","doi-asserted-by":"crossref","award":["RS-2025-02314076"],"award-info":[{"award-number":["RS-2025-02314076"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["DIGITAL HEALTH"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Amyotrophic lateral sclerosis (ALS) impairs oral motor function, negatively affecting patients\u2019 speech and swallowing abilities, as well as quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aims to evaluate the effectiveness of A Successful Swallowing with Effortful Training (ASSET) program, included in the \u2018The 365 Healthy Swallow Health Coach application\u2019 in preserving speech and swallowing abilities in ALS patients through self-training.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this 8-week quasi-experimental study, 13 participants were allocated to either the app-guided ASSET training group (n=7; three sessions per day, five days per week) or a usual-care control group (n=6) based on their clinical visit schedules. To evaluate changes over time and compare the two groups, linear mixed models were employed. Changes in ALS severity scale (ALSSS), Diadochokinetic (DDK) task, speech intensity, Speech Handicap Index-15, Dysphagia Handicap Index, Swallowing Quality of Life (SWAL-QOL), and Brief Inventory of Swallowing Assessment-15 were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>ALSSS speech scores was relatively preserved from 5.43 (95% CI 3.01\u20137.84) to 5.29 (95% CI 2.87\u20137.70) in the ASSET treatment group, but declined from 6.33 (95% CI 3.73\u20138.94) to 4.83 (95% CI 2.23\u20137.44) in the control group, with a significant group-by-time interaction (p=.017). DDK\/tuh\/and\/kuh\/were relatively preserved from 11.86 to 11.71 and from 12.29 to 11.57 respectively in ASSET group, but declined from 11.67 to 7.50 and from 11.83 to 7.17 in the control group, with significant interactions in\/tuh\/(p=.032) and\/kuh\/(p=.044). SWAL-QOL total score was relatively preserved from 155.86 to 149.71 in ASSET group, but declined from 154.67 to 125.17 in the control group, with a significant interaction (p=.011).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The findings suggest that ASSET program may help preserve speech and swallowing function in patients with ALS. Future research should validate the ASSET program with a larger, adequately powered sample size.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20552076261452405","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T13:17:31Z","timestamp":1778851051000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["The effects of a mobile healthcare application on speech and swallowing in amyotrophic lateral sclerosis"],"prefix":"10.1177","volume":"12","author":[{"given":"Yeongju","family":"Cho","sequence":"first","affiliation":[{"name":"Yonsei University College of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1257-9793","authenticated-orcid":false,"given":"Sun Young","family":"Won","sequence":"additional","affiliation":[{"name":"Yonsei University College of Medicine"},{"name":"Yonsei University College of Medicine"},{"name":"Department of Medicine, Graduate School of Yonsei University College of Medicine, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4949-2512","authenticated-orcid":false,"given":"Hyanghee","family":"Kim","sequence":"additional","affiliation":[{"name":"Yonsei University College of Medicine"},{"name":"Yonsei University College of Medicine"},{"name":"Yonsei University College of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1962-8630","authenticated-orcid":false,"given":"Hye Kyoung","family":"Lee","sequence":"additional","affiliation":[{"name":"Yonsei University College of Medicine"},{"name":"Yonsei University College of Medicine"},{"name":"Department of Medicine, Graduate School of Yonsei University College of Medicine, Seoul, Republic of Korea"},{"name":"Yonsei University College of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1429-2684","authenticated-orcid":false,"given":"Sung-Rae","family":"Cho","sequence":"additional","affiliation":[{"name":"Yonsei University College of Medicine"},{"name":"Yonsei University College of Medicine"},{"name":"Department of Medicine, Graduate School of Yonsei University College of Medicine, Seoul, Republic of Korea"},{"name":"Yonsei University College of Medicine"},{"name":"Yonsei University College of Medicine"},{"name":"Yonsei University College of Medicine"},{"name":"Yonsei University College of Medicine"},{"name":"Metabolism-Dementia Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,5,15]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.7748\/ns.26.46.48.s51"},{"key":"e_1_3_3_3_2","first-page":"1","article-title":"Amyotrophic lateral sclerosis","volume":"3","author":"Hardiman O","year":"2017","unstructured":"Hardiman O, Al-Chalabi A, Chio A, et al. 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