{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T21:56:59Z","timestamp":1781301419283,"version":"3.54.1"},"reference-count":33,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"the Ministry of Education, Culture, Sports, Science and Technology Grant-in-Aid for Scientific Research","award":["23H03885"],"award-info":[{"award-number":["23H03885"]}]},{"name":"the Ministry of Economy, Trade and Industry Subsidy for Demonstration Projects for Femtech and Similar Support Services"},{"name":"Joint research funding from YStory Inc"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["DIGITAL HEALTH"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      A self-care smartphone application,\n                      <jats:italic toggle=\"yes\">JoyHer Pro<\/jats:italic>\n                      , was developed to support midlife women experiencing menopausal symptoms by providing daily symptom tracking, personalized healthcare plan recommendations, and educational content. A proof-of-concept study was conducted to explore its feasibility and preliminary impact.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This single-arm pre\u2013post study simulated a health checkup\u2013based model of digital intervention. Ninety-one Japanese women aged 45\u201355 years with moderate menopausal symptoms used\n                      <jats:italic toggle=\"yes\">JoyHer Pro<\/jats:italic>\n                      for six months. The primary outcome was the change in total scores on the scaled Questionnaire for the Assessment of Climacteric Symptoms in Japanese Women (sQACS) from baseline to six months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The six-month follow-up rate was 96%. Participants recorded symptoms on a median of 165 days (90% of the study period) and logged self-care activities on 59% of days. They accessed a median of 42 educational topics (72% of available content). The total sQACS score significantly decreased from baseline to three and six months (both\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). Participants also reported improvements in their perception and attitude toward menopause, as well as greater self-assessed knowledge and coping ability. Some participants newly sought or planned medical consultation following app use.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This proof-of-concept study suggests that\n                      <jats:italic toggle=\"yes\">JoyHer Pro<\/jats:italic>\n                      is a feasible digital self-care support tool for midlife women with menopausal symptoms and may provide a basis for future research on integrating digital interventions into preventive care and public health strategies.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20552076261459996","type":"journal-article","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:12:37Z","timestamp":1781136757000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A self-care smartphone application for midlife women with menopausal symptoms: A proof-of-concept study"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7382-3313","authenticated-orcid":false,"given":"Takuma","family":"Ohsuga","sequence":"first","affiliation":[{"name":"Kyoto University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miho","family":"Egawa","sequence":"additional","affiliation":[{"name":"Kyoto University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaori","family":"Tsuyuki","sequence":"additional","affiliation":[{"name":"Kyoto University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miki","family":"Ohtsuki","sequence":"additional","affiliation":[{"name":"Kyoto University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wanjie","sequence":"additional","affiliation":[{"name":"YStory Inc"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi","family":"Juan","sequence":"additional","affiliation":[{"name":"YStory Inc"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rena","family":"Hinotani","sequence":"additional","affiliation":[{"name":"Kyoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshimitsu","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Kyoto University School of Public Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeo","family":"Nakayama","sequence":"additional","affiliation":[{"name":"Kyoto University School of Public Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Mandai","sequence":"additional","affiliation":[{"name":"Kyoto University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,10]]},"reference":[{"key":"e_1_3_8_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.4"},{"key":"e_1_3_8_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2015.05.001"},{"key":"e_1_3_8_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042192-200007030-00009"},{"key":"e_1_3_8_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2023.02.025"},{"key":"e_1_3_8_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000002028"},{"key":"e_1_3_8_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000002200"},{"key":"e_1_3_8_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/13697137.2025.2548806"},{"key":"e_1_3_8_9_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0245385"},{"key":"e_1_3_8_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmedr.2023.102467"},{"key":"e_1_3_8_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healthpol.2024.105122"},{"key":"e_1_3_8_12_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pdig.0000573"},{"key":"e_1_3_8_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2024.108005"},{"key":"e_1_3_8_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2023-077185"},{"key":"e_1_3_8_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-023-02463-4"},{"key":"e_1_3_8_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2024.108113"},{"key":"e_1_3_8_17_2","doi-asserted-by":"publisher","DOI":"10.2196\/63948"},{"key":"e_1_3_8_18_2","first-page":"756","article-title":"Menopausal disorders: menopausal index","volume":"76","author":"Koyama T","year":"1998","unstructured":"Koyama T. 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