{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T21:49:02Z","timestamp":1755035342735,"version":"3.41.2"},"reference-count":14,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis Journal - Experimental, Translational and Clinical"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> Clinical phenotypes of patients with antibodies to myelin oligodendrocyte glycoprotein (anti-MOG+) are unknown in India. <\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p> Retrospectively to characterise anti-MOG+ patients with inflammatory central nervous system disorders in India. <\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p> A total of 87 patients with non-multiple sclerosis demyelinating disorders (excluding acute disseminated encephalomyelitis) who were seronegative for anti-aquaporin 4 antibody were retrospectively analysed using a cell-based assay for anti-MOG+ status. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Twenty-five patients were anti-MOG+ in this cohort. They represented 28.7% (25\/87) of patients who tested negative for anti-AQP4+. Sixty-four per cent (16\/25) of anti-MOG+ patients were men and had a relapsing course. Patients with recurrent optic neuritis and those with a single attack of acute longitudinally extensive transverse myelitis were the most common phenotypes. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p> Relapsing optic neuritis was the most common phenotype, contrasting with a lower risk of relapses in transverse myelitis. <\/jats:p><\/jats:sec>","DOI":"10.1177\/2055217316675634","type":"journal-article","created":{"date-parts":[[2016,10,25]],"date-time":"2016-10-25T01:29:22Z","timestamp":1477358962000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Relapsing optic neuritis and isolated transverse myelitis are the predominant clinical phenotypes for patients with antibodies to myelin oligodendrocyte glycoprotein in India"],"prefix":"10.1177","volume":"2","author":[{"given":"Lekha","family":"Pandit","sequence":"first","affiliation":[{"name":"Department of Neurology, Nitte University, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas Kazutoshi","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Neurology\/Multiple Sclerosis Therapeutics, Tohoku University Graduate School of Medicine, Japan"},{"name":"Brain Institute, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharik","family":"Mustafa","sequence":"additional","affiliation":[{"name":"Department of Neurology, Nitte University, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiyuki","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Neurology, Yonezawa National Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anitha","family":"D\u2019Cunha","sequence":"additional","affiliation":[{"name":"Department of Neurology, Nitte University, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaithra","family":"Malli","sequence":"additional","affiliation":[{"name":"Department of Neurology, Nitte University, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akshatha","family":"Sudhir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Fujihara","sequence":"additional","affiliation":[{"name":"Department of Neurology\/Multiple Sclerosis Therapeutics, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,10,24]]},"reference":[{"doi-asserted-by":"publisher","key":"bibr1-2055217316675634","DOI":"10.1212\/WNL.0b013e31826aac4e"},{"doi-asserted-by":"publisher","key":"bibr2-2055217316675634","DOI":"10.1016\/j.jns.2013.08.034"},{"doi-asserted-by":"publisher","key":"bibr3-2055217316675634","DOI":"10.1212\/WNL.0000000000000101"},{"doi-asserted-by":"publisher","key":"bibr4-2055217316675634","DOI":"10.1212\/NXI.0000000000000040"},{"doi-asserted-by":"publisher","key":"bibr5-2055217316675634","DOI":"10.1186\/s12974-015-0256-1"},{"doi-asserted-by":"publisher","key":"bibr6-2055217316675634","DOI":"10.1177\/1352458515587751"},{"doi-asserted-by":"publisher","key":"bibr7-2055217316675634","DOI":"10.1177\/1352458515614093"},{"doi-asserted-by":"publisher","key":"bibr8-2055217316675634","DOI":"10.1212\/01.wnl.0000216139.44259.74"},{"doi-asserted-by":"publisher","key":"bibr9-2055217316675634","DOI":"10.1001\/archneurol.2011.2956"},{"doi-asserted-by":"publisher","key":"bibr10-2055217316675634","DOI":"10.1212\/NXI.0000000000000131"},{"doi-asserted-by":"publisher","key":"bibr11-2055217316675634","DOI":"10.1212\/WNL.0000000000001729"},{"doi-asserted-by":"publisher","key":"bibr12-2055217316675634","DOI":"10.1136\/jnnp-2014-310206"},{"doi-asserted-by":"publisher","key":"bibr13-2055217316675634","DOI":"10.1159\/000227277"},{"doi-asserted-by":"publisher","key":"bibr14-2055217316675634","DOI":"10.1001\/archneurol.2010.188"}],"container-title":["Multiple Sclerosis Journal - 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