{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T03:12:43Z","timestamp":1790824363218,"version":"4.1.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100007543","name":"Agence Nationale de S\u00e9curit\u00e9 du M\u00e9dicament et des Produits de Sant\u00e9","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis Journal - Experimental, Translational and Clinical"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> Most of the knowledge about people with multiple sclerosis (PwMS) in France comes from cohorts, which may suffer from recruitment bias or from the unique registry located in Lorraine, East France. <\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p> To describe use of care in the French population of PwMS, over 2010\u20132015. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> All PwMS in the French national health data system (97% of the general population covered) were included. Demographics, and use of care were described (visits with general practitioners (GPs), neurologists, nurses, physiotherapists and hospitalisations). A focus on the neurological follow-up was also conducted. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> A total of 112,415 PwMS were identified (sex ratio F:M\u2009=\u20092.4, median age 46), of whom 5005 died during follow-up. The median numbers of visits with GPs and neurologists were 6.6 and 1.3 respectively per patient-year. Moreover, 53,457 (47.6%) received multiple sclerosis (MS) treatments; about 13% of patients had no neurological follow-up, and 81.8% had at least one hospitalisation. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> For the first time in France, this exhaustive dataset offered the opportunity to provide objective figures regarding care practices for MS at the national level, without any selection bias. It also allowed description of patients with MS according to their neurological follow-up, especially those who were absent from cohorts led by neurologists. <\/jats:p><\/jats:sec>","DOI":"10.1177\/2055217319896090","type":"journal-article","created":{"date-parts":[[2019,12,18]],"date-time":"2019-12-18T14:32:54Z","timestamp":1576679574000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Use of healthcare services by patients with multiple sclerosis in France over 2010\u20132015: a nationwide population-based study using health administrative data"],"prefix":"10.1177","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0158-2837","authenticated-orcid":false,"given":"J.","family":"Roux","sequence":"first","affiliation":[{"name":"Univ Rennes, EHESP, REPERES (Pharmacoepidemiology and health services research-EA 7449), Rennes, France"},{"name":"Univ Rennes, CHU Rennes, Inserm, CIC (Centre d\u2019Investigation Clinique de Rennes), Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Guilleux","sequence":"additional","affiliation":[{"name":"Univ Rennes, EHESP, REPERES (Pharmacoepidemiology and health services research-EA 7449), Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Lefort","sequence":"additional","affiliation":[{"name":"Univ Rennes, EHESP, REPERES (Pharmacoepidemiology and health services research-EA 7449), Rennes, France"},{"name":"Univ Rennes, CHU Rennes, Inserm, CIC (Centre d\u2019Investigation Clinique de Rennes), Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Leray","sequence":"additional","affiliation":[{"name":"Univ Rennes, EHESP, REPERES (Pharmacoepidemiology and health services research-EA 7449), Rennes, France"},{"name":"Univ Rennes, CHU Rennes, Inserm, CIC (Centre d\u2019Investigation Clinique de Rennes), Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,12,18]]},"reference":[{"key":"bibr1-2055217319896090","unstructured":"MS International Federation. 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