{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T19:34:13Z","timestamp":1775072053989,"version":"3.50.1"},"reference-count":30,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007379","name":"Fondation pour l'Aide \u00e0 la Recherche sur la Scl\u00e9rose en Plaques","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007379","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis Journal - Experimental, Translational and Clinical"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> Mental disorders (MDs) in multiple sclerosis (MS) patients decreases treatment adherence and quality of life, and increases the risk of disability progression and care consumption. <\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p> This study was to assess the prevalence of MDs in MS patients compared with healthy controls (HC) of the French general population and rheumatoid arthritis (RA) patients. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> The 2015 prevalence of MDs for MS patients, RA patients and general population was estimated using a random population-based data sample from \u2018National Inter-Scheme Information System on Health Insurance\u2019 in the 2011\u20132015 period. Two control groups (1:5 ratio for the HC and 1:1 for the RA group) were matched to the MS group for year of birth, gender, area of residence and health insurance scheme. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> A total of 1145 MS patients were identified (sex ratio of 2.5 (F\/M); median age 50 years). The prevalence of MDs was higher in the population of patients with MS (37.3%) than in the French general population (13.6%), and to a lesser extent in the RA group (21.1%) leading to the prevalence ratios of 2.8 (95% confidence intervals (CIs) 2.5\u20133.0) and 1.9 (95% CI 1.7\u20132.3), respectively. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> This study confirmed that MS patients are at a higher risk of MDs than the French general population or RA patients. <\/jats:p><\/jats:sec>","DOI":"10.1177\/2055217320941540","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T17:13:48Z","timestamp":1598548428000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Prevalence of mental disorders is higher in patients with multiple sclerosis than in the general population or in patients with rheumatoid arthritis in France"],"prefix":"10.1177","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7952-6261","authenticated-orcid":false,"given":"Alice","family":"Guilleux","sequence":"first","affiliation":[{"name":"EHESP, REPERES, University of Rennes, France."},{"name":"Centre d\u2019Investigation Clinique de Rennes, University of Rennes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0158-2837","authenticated-orcid":false,"given":"Jonathan","family":"Roux","sequence":"additional","affiliation":[{"name":"EHESP, REPERES, University of Rennes, France"},{"name":"EHESP, REPERES, University of Rennes, France."},{"name":"Centre d\u2019Investigation Clinique de Rennes, University of Rennes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Travers","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University Hospital CHU Pontchaillou, France."},{"name":"EHESP, REPERES, University of Rennes, France."},{"name":"Centre d\u2019Investigation Clinique de Rennes, University of Rennes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuelle","family":"Leray","sequence":"additional","affiliation":[{"name":"EHESP, REPERES, University of Rennes, France."},{"name":"Centre d\u2019Investigation Clinique de Rennes, University of Rennes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,8,27]]},"reference":[{"key":"bibr1-2055217320941540","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000768"},{"key":"bibr2-2055217320941540","doi-asserted-by":"crossref","unstructured":"Scalfari A, Knappertz V, Cutter G, Goodin DS, Ashton R, Ebers GC. Mortality in patients with multiple sclerosis. 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