{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:29:29Z","timestamp":1761920969519,"version":"3.41.2"},"reference-count":6,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis Journal - Experimental, Translational and Clinical"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:p> Myelin oligodendrocyte-antibody-associated disease (MOGAD) often presents with severe optic neuritis (ON) but tends to recover better than in aquaporin-4 antibody neuromyelitis optica spectrum disorder (AQP4-NMOSD). We measured OCT and VEP in MOGAD and AQP4-NMOSD eyes with good visual function, with or without previous ON episodes. Surprisingly, OCT and\/or VEPs were abnormal in 84% MOGAD-ON versus 38% AQP4-NMOSD-ON eyes (p\u2009=\u20090.009) with good vision, compared with 18% and 17% respectively of eyes with no previous ON. A sub-group with macular OCT performed as part of a research study confirmed both retinal and macular defects in visually-recovered MOGAD eyes. These findings have implications for investigation and management of MOGAD patients. <\/jats:p>","DOI":"10.1177\/20552173211066446","type":"journal-article","created":{"date-parts":[[2021,12,22]],"date-time":"2021-12-22T13:16:39Z","timestamp":1640178999000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["The use of OCT in good visual acuity MOGAD and AQP4-NMOSD patients; with and without optic neuritis"],"prefix":"10.1177","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8720-9397","authenticated-orcid":false,"given":"A","family":"Roca-Fern\u00e1ndez","sequence":"first","affiliation":[{"name":"Nuffield Department of Clinical Neuroscience, University Of Oxford, UK"},{"name":"Department of Neurology\/Neuroimmunology, Multiple Sclerosis Centre of Catalonia (CEMCAT), Hospital Universitari Vall d'Hebron, Universitat Aut\u00f2noma de Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Camera","sequence":"additional","affiliation":[{"name":"Nuffield Department of Clinical Neuroscience, University Of Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Loncarevic-Whitaker","sequence":"additional","affiliation":[{"name":"University of Oxford Clinical Medical School, Medical Science Division, University of Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1134-5771","authenticated-orcid":false,"given":"S","family":"Messina","sequence":"additional","affiliation":[{"name":"Nuffield Department of Clinical Neuroscience, University Of Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Mariano","sequence":"additional","affiliation":[{"name":"Nuffield Department of Clinical Neuroscience, University Of Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Vincent","sequence":"additional","affiliation":[{"name":"Nuffield Department of Clinical Neuroscience, University Of Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Oxford University Hospitals, National Health Service Trust, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MI","family":"Leite","sequence":"additional","affiliation":[{"name":"Nuffield Department of Clinical Neuroscience, University Of Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Palace","sequence":"additional","affiliation":[{"name":"Nuffield Department of Clinical Neuroscience, University Of Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,12,22]]},"reference":[{"key":"bibr1-20552173211066446","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awx276"},{"key":"bibr2-20552173211066446","doi-asserted-by":"publisher","DOI":"10.1111\/j.1759-1961.2012.00030.x"},{"volume":"11","journal-title":"Front Neurol [Internet]","author":"Filippatou AG","key":"bibr3-20552173211066446"},{"key":"bibr4-20552173211066446","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000005560"},{"key":"bibr5-20552173211066446","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aws109"},{"key":"bibr6-20552173211066446","doi-asserted-by":"publisher","DOI":"10.1177\/1352458519864928"}],"container-title":["Multiple Sclerosis Journal - Experimental, Translational and Clinical"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20552173211066446","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/20552173211066446","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20552173211066446","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,25]],"date-time":"2025-01-25T06:13:04Z","timestamp":1737785584000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/20552173211066446"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":6,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1177\/20552173211066446"],"URL":"https:\/\/doi.org\/10.1177\/20552173211066446","relation":{},"ISSN":["2055-2173","2055-2173"],"issn-type":[{"type":"print","value":"2055-2173"},{"type":"electronic","value":"2055-2173"}],"subject":[],"published":{"date-parts":[[2021,10]]},"article-number":"20552173211066446"}}