{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T09:03:53Z","timestamp":1775293433234,"version":"3.50.1"},"reference-count":24,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["U19AG078109"],"award-info":[{"award-number":["U19AG078109"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["UH2\/UH3AG083264"],"award-info":[{"award-number":["UH2\/UH3AG083264"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis Journal \u2013 Experimental, Translational and Clinical"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Patient-Determined Disease Steps (PDDS) and Neuro-QoL Lower Extremity Function\u2014Short Form (Neuro-QoL LEF-SF) are patient-reported outcome measures used to monitor mobility symptoms in multiple sclerosis (MS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To develop and validate a crosswalk between the PDDS and Neuro-QoL LEF-SF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using equipercentile equating, we created a crosswalk from a training sample of 619 MS patients (mean PDDS = 2.4\u2009\u00b1\u20092.3; mean Neuro-QoL LEF-SF\u2009=\u200933.0\u2009\u00b1\u20098.3). Validation was performed in a separate sample of 147 MS patients (mean PDDS = 0.6\u2009\u00b1\u20091.2; mean Neuro-QoL LEF-SF\u2009=\u200938.9\u2009\u00b1\u20092.8). Agreement between original and converted scores was evaluated using paired t-tests and concordance correlation coefficients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      PDDS and Neuro-QoL LEF-SF scores were strongly correlated in both training (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      \u2009=\u2009\u22120.89) and validity (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      \u2009=\u2009\u22120.76) samples. No significant differences in change scores were observed. Concordance coefficients of original and converted scores supported good to very good agreement.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We developed a crosswalk for the conversion of scores between the PDDS and the Neuro-QoL LEF-SF for patients with MS. Evidence for the preliminary validity of this crosswalk was demonstrated with both the initial training sample and a separate validity sample. This crosswalk facilitates score comparisons and data harmonization across studies and clinical registries using either measure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20552173261427107","type":"journal-article","created":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T11:33:33Z","timestamp":1775129613000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Measurement of functional mobility in multiple sclerosis: A crosswalk between the patient-determined disease steps and the Neuro-QoL Lower Extremity Function\u2014Short Form"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7842-4220","authenticated-orcid":false,"given":"Alexa S","family":"Gonzalez","sequence":"first","affiliation":[{"name":"University of Houston"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4459-3576","authenticated-orcid":false,"given":"Joshua M","family":"Garcia","sequence":"additional","affiliation":[{"name":"University of Houston"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8875-5521","authenticated-orcid":false,"given":"Eric","family":"Engebretson","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Colorado Anschutz Medical Campus"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8163-7772","authenticated-orcid":false,"given":"Luis D","family":"Medina","sequence":"additional","affiliation":[{"name":"University of Houston"},{"name":"Baylor College of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,2]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1185\/03007990903433528"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2019.05.019"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2021.103475"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000821"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-024-03871-1"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.2.251"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.7224\/1537-2073.2021-102"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2025.106391"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318258f744"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/2055217319885986"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/s41687-024-00743-7"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-13-37"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.2.251"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/01376517-200712000-00005"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458515599450"},{"key":"e_1_3_3_17_2","unstructured":"R Core Team. R: A language and environment for statistical computing. https:\/\/www.R-project.org\/. 2022."},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1207\/s15324818ame0301_2"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v074.i08"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.86.2.420"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1201\/9780429258589"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.4324\/9780203771587"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-011-0040-3"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458519852722"},{"key":"e_1_3_3_25_2","article-title":"The patient-determined disease steps scale is not interchangeable with the expanded disease Status scale in mild to moderate multiple sclerosis","volume":"31","author":"Foong YC","year":"2023","unstructured":"Foong YC, Merlo D, Gresle M, et al. The patient-determined disease steps scale is not interchangeable with the expanded disease Status scale in mild to moderate multiple sclerosis. 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