{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:45:23Z","timestamp":1777945523469,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Chicago Chronic Conditions Engagement Network","award":["5P50MD017349"],"award-info":[{"award-number":["5P50MD017349"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis Journal \u2013 Experimental, Translational and Clinical"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There is limited evidence on the feasibility of remotely delivered exercise interventions for English-speaking Hispanics\/Latinos with MS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the feasibility and exploratory efficacy of a remotely-delivered, home-based exercise program for English-speaking Hispanics\/Latinos with MS and to explore associations among feasibility metrics, outcomes, and social determinants of health (SDOH).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 340 individuals contacted, 112 were eligible (33%), 33 enrolled (9.7%), 30 randomized, and 26 completed (87% retention). Adherence averaged 81% (exercise) and 89% (control). No serious adverse events occurred. Exploratory within-group improvements were observed in the exercise group for physical activity (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.03,\n                      <jats:italic toggle=\"yes\">d<\/jats:italic>\n                      \u2009=\u20090.66). Mobility improved by 10.1 points on the MS Walking Scale\u201312, exceeding the minimal clinically important difference. Exploratory analyses indicated that higher education correlated with greater program compliance (\n                      <jats:italic toggle=\"yes\">\u03c1<\/jats:italic>\n                      =0.70,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.005) and lower anxiety (\n                      <jats:italic toggle=\"yes\">\u03c1<\/jats:italic>\n                      =-0.69,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.006).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our results support the feasibility, safety, and preliminary benefits of remotely-delivered, home-based exercise training for improvements in physical activity and mobility for English-speaking Hispanics\/Latinos with MS. Exploratory results warrant evaluation in larger, adequately powered trials.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Trial Registration<\/jats:title>\n                    <jats:p>ClinicalTrials.gov (NCT05998616).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20552173261448001","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T13:05:22Z","timestamp":1777554322000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility and preliminary outcomes of a remotely-delivered exercise training intervention for English-speaking Hispanics\/Latinos with multiple sclerosis: Results from the FERLA MS study"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2686-4603","authenticated-orcid":false,"given":"Victoria 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Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Augusto","family":"Miravalle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9673-644X","authenticated-orcid":false,"given":"Fabian","family":"Sierra-Morales","sequence":"additional","affiliation":[{"name":"Rush University Medical Center, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5894-2290","authenticated-orcid":false,"given":"Robert W","family":"Motl","sequence":"additional","affiliation":[{"name":"University of Illinois 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