{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T14:20:19Z","timestamp":1780323619609,"version":"3.54.1"},"reference-count":15,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100004328","name":"Genentech","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004328","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis Journal \u2013 Experimental, Translational and Clinical"],"published-print":{"date-parts":[[2026,4]]},"abstract":"\n Objectives<\/jats:title>\n To assess hematologic abnormalities in breastfed infants of mothers with multiple sclerosis (MS) receiving anti-CD20 therapies.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Breastfed infants with maternal anti-CD20 use were identified. Infant blood draws examined B-cell (CD19) and hematological counts.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Nine of 10 identified infants had CD19 percentages in ranges expected for age. One infant had CD19 levels below the 5\n th<\/jats:sup>\n percentile but was interpreted by their treating pediatrician as normal for age, with no increase in infections reported.\n <\/jats:p>\n <\/jats:sec>\n \n Discussion<\/jats:title>\n The absence of significant CD19 abnormalities in our cohort may indicate infant hematology safety. This may allow mothers MS to utilize anti-CD20 therapies while breastfeeding.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/20552173261454808","type":"journal-article","created":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T15:15:48Z","timestamp":1780154148000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Absence of significant hematologic abnormalities in breastfed infants of mothers with multiple sclerosis treated with anti-CD20 therapies"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0580-0248","authenticated-orcid":false,"given":"Anna","family":"Shah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5854-9643","authenticated-orcid":false,"given":"Enrique","family":"Alvarez","sequence":"additional","affiliation":[{"name":"Rocky Mountain MS Center, Department of Neurology, University of Colorado School of Medicine, Aurora, CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,30]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000006384"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2020.102541"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh152"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000959"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000009374"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2019.4173"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000637"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000769"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000723"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000200264"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000211193"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.51893"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000200349"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2022-329545"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2022.06.006"}],"container-title":["Multiple Sclerosis Journal \u2013 Experimental, Translational and Clinical"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20552173261454808","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/20552173261454808","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20552173261454808","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T13:17:34Z","timestamp":1780319854000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/20552173261454808"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1177\/20552173261454808"],"URL":"https:\/\/doi.org\/10.1177\/20552173261454808","relation":{},"ISSN":["2055-2173","2055-2173"],"issn-type":[{"value":"2055-2173","type":"print"},{"value":"2055-2173","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"article-number":"20552173261454808"}}