{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T02:26:15Z","timestamp":1788575175907,"version":"build-2803163510"},"reference-count":37,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"medical reserach foundation of oregon","award":["AOTOL0328"],"award-info":[{"award-number":["AOTOL0328"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Rehabilitation and Assistive Technologies Engineering"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Electric stimulation (ES) can prevent muscle atrophy and promote tissue healing and therefore may help prevent sequelae of Bell\u2019s palsy but due to lack of high-quality studies, the effectiveness of ES in Bell\u2019s palsy remains controversial. Here we describe a protocol to evaluate the effects of monophasic high volt ES in patients with Bell\u2019s palsy and poor prognosis for recovery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This is a protocol for a prospective, double-blinded, randomized, placebo-controlled study. Participants include adults with acute Bell\u2019s palsy with poor prognosis for full recovery due to complete paralysis or being over age 60. ES will be a monophasic, high-volt pulsed waveform, 100\u03bcsec pulse duration, 35\u2009hertz, motor-level intensity. Follow up will be at months 1, 2, 3 and 6. The primary outcome will be the proportion of patients with complete recovery using the eFACES tool. Secondary outcomes include patient reported quality of life measured by FaCE and the synkinesis assessment questionnaires, objective photographs, time to complete recovery, adverse effects, and tolerability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This protocol has the potential to provide high quality evidence regarding the effects, up to 6\u2009months after onset, of pulsed monophasic high-volt ES for patients with acute Bell\u2019s palsy and poor prognosis for complete recovery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2055668320964142","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T14:03:40Z","timestamp":1607609020000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Protocol for randomized controlled trial of electric stimulation with high-volt twin peak versus placebo for facial functional recovery from acute Bell\u2019s palsy in patients with poor prognostic factors"],"prefix":"10.1177","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1590-7054","authenticated-orcid":false,"given":"Myriam","family":"Loyo","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery, Oregon Health & Science University, Portland, OR, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"McReynold","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Oregon Health & Science University, Portland, OR, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jess C","family":"Mace","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery, Oregon Health & Science University, Portland, OR, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Cameron","sequence":"additional","affiliation":[{"name":"Department of Neurology, Oregon Health & Science University, Oregon Health & Science University, Portland, OR, USA"},{"name":"VA Portland Health Care System, Oregon Health & Science University, Portland, OR, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,12,10]]},"reference":[{"key":"bibr1-2055668320964142","doi-asserted-by":"publisher","DOI":"10.1177\/014556139607500608"},{"key":"bibr2-2055668320964142","first-page":"1204","volume":"2014","author":"Holland NJ","year":"2014","journal-title":"BMJ Clin 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