{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T05:55:40Z","timestamp":1778824540512,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiologica Open"],"published-print":{"date-parts":[[2022,8]]},"abstract":"\n Background<\/jats:title>\n Dual-energy contrast-enhanced mammography (DECEM) is an advanced breast imaging technique of digital mammography.<\/jats:p>\n <\/jats:sec>\n \n Purpose<\/jats:title>\n To assess the total radiation dose received from complete DECEM using different combinations of exposure parameters for low- and high-energy images.<\/jats:p>\n <\/jats:sec>\n \n Materials and methods<\/jats:title>\n \n A dedicated phantom with three different concentrations of iodine inserts was used. Each iodine insert was 10\u00a0mm in diameter and concentration of 1.0\u00a0mgI\/cm\n 3<\/jats:sup>\n , 2.0\u00a0mgI\/cm\n 3<\/jats:sup>\n , and 4.0\u00a0mgI\/cm\n 3<\/jats:sup>\n . The phantom was exposed at varying kVp levels. Mean glandular dose (MGD) was estimated. Contrast to noise ratio (CNR) and figure of merit (FOM) of the iodine inserts were used to assess the image quality.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The optimum CNR of the recombined images was obtained by using 28\u00a0kVp + 49\u00a0kVp tube voltage combination for 50\u00a0mm thickness, 50% fibroglandular phantom only with a 26% dose increase compared to the highest voltages (32\u00a0kVp + 49\u00a0kVp) that can be used for low energy (LE) and high energy (HE) imaging. The CNR value was increased with increasing iodine concentration ( R\n 2<\/jats:sup>\n > 0.99).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The use of as low as possible tube voltage for the LE imaging of standard 50% fibroglandular\u201350% adipose, 50\u00a0mm thickness breast while using the highest tube voltage for HE imaging has reduced the MGD while keeping optimum image quality.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/20584601221117251","type":"journal-article","created":{"date-parts":[[2022,8,11]],"date-time":"2022-08-11T09:30:58Z","timestamp":1660210258000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of exposure factors of dual-energy contrast-enhanced mammography to optimize radiation dose with improved image quality"],"prefix":"10.1177","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9705-9759","authenticated-orcid":false,"given":"Sachila","family":"Niroshani","sequence":"first","affiliation":[{"name":"Department of Radiological Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan"},{"name":"Department of Radiography and Radiotherapy, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2124-3186","authenticated-orcid":false,"given":"Tokiko","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Radiological Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan"},{"name":"Department of Radiology, Juntendo University Shizuoka Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikaidou","family":"Michiru","sequence":"additional","affiliation":[{"name":"Department of Radiological Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toru","family":"Negishi","sequence":"additional","affiliation":[{"name":"Department of Radiological Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,8,11]]},"reference":[{"key":"bibr1-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2251011667"},{"key":"bibr2-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2283020961"},{"key":"bibr3-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1097\/01.rli.0000167421.83203.4e"},{"key":"bibr4-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2009.10.002"},{"key":"bibr5-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1186\/bcr3210"},{"key":"bibr6-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2008.07.035"},{"key":"bibr7-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.12121084"},{"key":"bibr8-20584601221117251","doi-asserted-by":"publisher","DOI":"10.21037\/qims.2019.10.13"},{"key":"bibr9-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1118\/1.1510128"},{"key":"bibr10-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-015-3695-2"},{"key":"bibr11-20584601221117251","doi-asserted-by":"publisher","DOI":"10.2217\/WHE.14.18"},{"key":"bibr12-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-010-1944-y"},{"key":"bibr13-20584601221117251","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.16.16743"},{"key":"bibr14-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1097\/RLI.0000000000000068"},{"key":"bibr15-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1016\/j.diii.2013.10.002"},{"key":"bibr16-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1093\/rpd\/ncv098"},{"key":"bibr17-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-07887-8_56"},{"key":"bibr18-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/45\/11\/308"},{"key":"bibr19-20584601221117251","volume-title":"European Commission. S1 digital mammography update European guidelines for quality assurance in breast cancer screening and diagnosis","author":"Amendoeira I","year":"2013","edition":"4"},{"key":"bibr20-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1117\/1.JMI.1.3.033506"},{"key":"bibr21-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-015-3693-2"},{"key":"bibr22-20584601221117251","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-006-0574-x"}],"container-title":["Acta Radiologica Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20584601221117251","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/20584601221117251","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20584601221117251","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:54:55Z","timestamp":1777377295000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/20584601221117251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":22,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1177\/20584601221117251"],"URL":"https:\/\/doi.org\/10.1177\/20584601221117251","relation":{},"ISSN":["2058-4601","2058-4601"],"issn-type":[{"value":"2058-4601","type":"print"},{"value":"2058-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8]]},"article-number":"20584601221117251"}}