{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:05:32Z","timestamp":1790690732710,"version":"4.1.0"},"reference-count":28,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiologica Open"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Uterine cavity pathology may affect the endometrium or myometrium, resulting in distortion of the uterine cavity, and is responsible for 2%\u20135% of infertility. The methods for its assessment usually involve imaging modalities like pelvic ultrasonography, often transvaginal-(TVS), and hysterosalpingography-(HSG), with hysteroscopy-(HSC) as the gold standard. However, HSC is not readily available in resource-poor-settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To determine and compare the diagnostic accuracy of TVS and HSG in detecting uterine cavity pathology using HSC as a gold standard.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A cross-sectional analytical study of consenting infertile women for evaluation of the uterine cavity using transvaginal-ultrasonography, hysterosalpingogram, and hysteroscopy. The primary-outcome-measures were the sensitivity, specificity, and accuracy of TVS and HSG in detecting uterine cavity abnormalities using HSG as the gold standard.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighty-eight participants were analysed for this study. The lesions confirmed on HSC were intrauterine-adhesions (43.1%), endometrial polyps (14.8%), submucous fibroids (18.2%), intrauterine-septum (13.6%), and cavity distortion (14.8%). The overall sensitivity with TVS was 57.7%, with a specificity of 97.6%, a positive-predictive-value (PPV) of 88.2%, and a negative-predictive-value (NPV) of 88.2%, giving a percentage-accuracy of 88.2%. In comparison, HSG had a sensitivity of 72.1%, a specificity of 99.4%, a PPV of 97.4%, and an NPV of 92.0%, giving an overall accuracy of 92.9%. The detection rates of TVS and HSG in this category were: fibroids (97.7% vs 89.8%; p = .0004) and adhesions (73.9% vs 87.5%; p = .0002), respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>HSG appears to be the superior modality for detection of obliterative uterine cavity pathologies, while TVS is better suited for myometrium and endometrial lesions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20584601241252335","type":"journal-article","created":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T03:54:50Z","timestamp":1715313290000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Diagnostic accuracy of transvaginal ultrasonography and hysterosalpingography in the detection of uterine cavity pathologies among infertile women"],"prefix":"10.1177","volume":"13","author":[{"given":"Ifeanyi O","family":"Okonkwo","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George U","family":"Eleje","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"},{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Awka, Awka, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nworah J","family":"Obiechina","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"},{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Awka, Awka, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph O","family":"Ugboaja","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"},{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Awka, Awka, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chisolum O","family":"Okafor","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nnamdi Azikiwe University Awka, Awka, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikechukwu I","family":"Mbachu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"},{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Awka, Awka, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hillary I","family":"Obiagwu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayodele O","family":"Okwuosa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel N","family":"Onwusulu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"},{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Awka, Awka, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chukwunwendu F","family":"Okeke","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"},{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Awka, Awka, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chukwuemeka J","family":"Ofojebe","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"},{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Awka, Awka, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chidinma C","family":"Okafor","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Leicestershire Partnership NHS Trust, Leicester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chukwudi A","family":"Ogabido","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"},{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Awka, Awka, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chinedu L","family":"Olisa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4458-8216","authenticated-orcid":false,"given":"Chigozie G","family":"Okafor","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,5,10]]},"reference":[{"key":"bibr1-20584601241252335","unstructured":"Puscheck EE, Lucidi RS, Woodard TL. 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