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A significant number of patients require surgery for the definitive diagnosis and resolution of symptoms. We put forward a case of eosinophilic cholangiopathy infiltrating the gallbladder and bile duct with bone marrow involved, coupled with peripheral eosinophilia. The patient underwent a successful treatment using laparoscopic cholecystectomy and steroids, instead of extrahepatic bile duct excision with Roux-en-Y hepaticojejunostomy. The patient gets an accurate treatment in a minimally invasive manner. In conclusion, surgery refers to not only a diagnostic methodology but also a treatment. When the bile duct and gallbladder are involved at the same time, and cannot distinguish benign and malignant diseases, laparoscopic cholecystectomy is feasible, the effect is the same, and the symptoms of eosinophilic cholecystitis are relieved.<\/jats:p>","DOI":"10.1177\/2058738420941752","type":"journal-article","created":{"date-parts":[[2020,7,20]],"date-time":"2020-07-20T03:46:33Z","timestamp":1595216793000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A rare case of eosinophilic cholangiopathy"],"prefix":"10.1177","volume":"34","author":[{"given":"Wenya","family":"Li","sequence":"first","affiliation":[{"name":"Wenzhou Medical University, Wenzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feizhao","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of General Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 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