{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T10:24:58Z","timestamp":1759400698109,"version":"3.41.2"},"reference-count":11,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Scars, Burns &amp; Healing"],"published-print":{"date-parts":[[2016,1,1]]},"abstract":"<jats:p> [Formula: see text] <\/jats:p><jats:sec><jats:title>Introduction:<\/jats:title><jats:p> Globally, many burns units moved away from colloid resuscitation in response to the Cochrane review (1998). Recent literature has introduced the concept of fluid creep: patients receiving volumes far in excess of the upper limit of the Parkland formula. The Cochrane review has been widely criticised, however, and we continued to use 4.5% human albumin solution after 8 h of crystalloid as a hybrid of Parkland and Muir &amp; Barclay\u2019s regime. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> Adult patients \u2a7e15% TBSA were identified from data prospectively entered into our database over a 5-year period (2003\u20132008). Medical notes and intensive care charts were reviewed comparing volumes of fluids received with requirement estimates. Adverse events were also documented. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> A total of 72 cases with 34 sets of intensive care charts were analysed. Mean TBSA was 35.2% (range, 15\u201395%). A total of 75% survived; 3% were haemofiltered. Forty-one percent of patients were resuscitated using the Parkland formula alone, while 59% switched at 8 h post burn to the Muir and Barclay formula (Hybrid group). There was a significantly greater TBSA in the Hybrid group, but they received significantly less fluid volumes than the Parkland group ( P = 0.0363; the Hybrid group received 1.36 times calculated need vs. 1.62 in the Parkland group). <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> Our patients still demonstrate fluid creep, but to a lesser extent than previously reported. Fluid creep has been mitigated but not eliminated through this strategy. <\/jats:p><\/jats:sec>","DOI":"10.1177\/2059513116642083","type":"journal-article","created":{"date-parts":[[2016,4,23]],"date-time":"2016-04-23T02:08:21Z","timestamp":1461377301000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Albumin resuscitation in burns: a hybrid regime to mitigate fluid creep"],"prefix":"10.1177","volume":"2","author":[{"given":"Judith E","family":"Hunter","sequence":"first","affiliation":[{"name":"Welsh Centre for Burns and Plastic Surgery, Swansea, UK"},{"name":"Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter J","family":"Drew","sequence":"additional","affiliation":[{"name":"Welsh Centre for Burns and Plastic Surgery, Swansea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom S","family":"Potokar","sequence":"additional","affiliation":[{"name":"Welsh Centre for Burns and Plastic Surgery, Swansea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Dickson","sequence":"additional","affiliation":[{"name":"Welsh Centre for Burns and Plastic Surgery, Swansea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah J","family":"Hemington-Gorse","sequence":"additional","affiliation":[{"name":"Welsh Centre for Burns and Plastic Surgery, Swansea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,4,22]]},"reference":[{"key":"bibr1-2059513116642083","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.317.7153.235"},{"issue":"4","key":"bibr2-2059513116642083","first-page":"CD000567","author":"Perel P","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"volume-title":"Burns and their treatment","year":"1974","author":"Muir IA","key":"bibr3-2059513116642083"},{"key":"bibr4-2059513116642083","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1968.tb14738.x"},{"key":"bibr5-2059513116642083","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-200009000-00030"},{"key":"bibr6-2059513116642083","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2004.01.021"},{"key":"bibr7-2059513116642083","doi-asserted-by":"publisher","DOI":"10.1097\/00004630-200207000-00006"},{"key":"bibr8-2059513116642083","doi-asserted-by":"publisher","DOI":"10.1097\/BCR.0b013e3181cb8c72"},{"key":"bibr9-2059513116642083","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e3181ac68cf"},{"key":"bibr10-2059513116642083","doi-asserted-by":"publisher","DOI":"10.1097\/BCR.0b013e31825b1cf6"},{"issue":"2","key":"bibr11-2059513116642083","first-page":"59","volume":"25","author":"Atiyeh BS","year":"2012","journal-title":"Ann Burns Fire Disasters"}],"container-title":["Scars, Burns &amp; Healing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2059513116642083","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2059513116642083","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2059513116642083","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T22:15:46Z","timestamp":1740780946000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2059513116642083"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,1]]},"references-count":11,"alternative-id":["10.1177\/2059513116642083"],"URL":"https:\/\/doi.org\/10.1177\/2059513116642083","relation":{},"ISSN":["2059-5131","2059-5131"],"issn-type":[{"type":"print","value":"2059-5131"},{"type":"electronic","value":"2059-5131"}],"subject":[],"published":{"date-parts":[[2016,1,1]]},"article-number":"2059513116642083"}}