{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:43:59Z","timestamp":1777859039981,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Prim Care Community Health"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Brucellosis is the second most widely spread zoonotic disease. There is less literature on this disease in Pakistan, leading to delayed diagnosis, or the patient remains undiagnosed. This study aims to contribute to Pediatric brucellosis literature, epidemiological, clinical features, laboratory findings, and treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation:<\/jats:title>\n                    <jats:p>We present an 11-year-old child who was admitted to the hospital due to abdominal pain for one month and a fever for 15\u2009days. On abdominal ultrasound, she had hepato-splenomegaly with minimal pleural effusion. A comprehensive diagnostic workup for infectious and immunologic disorders confirmed brucellosis with the antibody tests report. She received doxycycline, rifampin, and trimethoprim-sulfamethoxazole for three months. The treatment was continued with Syrup Doxycycline (50\u2009mg\/5\u2009ml), and Syrup Rifampicin (2\u2009g\/100\u2009ml) was prescribed for five weeks. Her symptoms were improved by the end of the treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Brucella is an intracellular pathogen affecting multi-systems of the human body; thus, the treatment is started with antimicrobials that have penetrative effects on a cell. The treatment can be adjusted based on the age group and the complication of the symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21501319231170497","type":"journal-article","created":{"date-parts":[[2023,5,6]],"date-time":"2023-05-06T07:30:13Z","timestamp":1683358213000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Pediatric Brucellosis: A Challenging Diagnosis\u2014Case Report"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0469-2780","authenticated-orcid":false,"given":"Areeba","family":"Shaikh","sequence":"first","affiliation":[{"name":"Dr Ziauddin Hospital Clifton Karachi, Kar\u0101chi, Sindh, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Munira","family":"Sarfaraz","sequence":"additional","affiliation":[{"name":"Dr Ziauddin Hospital Clifton Karachi, Kar\u0101chi, Sindh, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaista","family":"Ehsan","sequence":"additional","affiliation":[{"name":"Dr Ziauddin Hospital Clifton Karachi, Kar\u0101chi, Sindh, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,5,6]]},"reference":[{"key":"bibr1-21501319231170497","unstructured":"Cureus. Brucellosis in Saudi Children: Presentation, complications, and treatment outcome. 2020. Accessed July 24, 2022. https:\/\/www.cureus.com\/articles\/44261-brucellosis-in-saudi-children-presentation-complications-and-treatment-outcome"},{"key":"bibr2-21501319231170497","doi-asserted-by":"publisher","DOI":"10.5455\/JPMA.24139"},{"key":"bibr3-21501319231170497","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofw263"},{"key":"bibr4-21501319231170497","doi-asserted-by":"publisher","DOI":"10.1016\/S1201-9712(02)90108-6"},{"key":"bibr5-21501319231170497","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001929"},{"key":"bibr6-21501319231170497","doi-asserted-by":"crossref","unstructured":"Ulu\u011f M, Yaman Y, Yapici F, Can-Ulu\u011f N. Clinical and laboratory features, complications and treatment outcome of brucellosis in childhood and review of the literature. Turk J Pediatr. 2011;53(4):413-424. https:\/\/pubmed.ncbi.nlm.nih.gov\/21980844\/","DOI":"10.24953\/turkjped.2011.1793"},{"key":"bibr7-21501319231170497","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2021.660508"},{"key":"bibr8-21501319231170497","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2015.03.003"},{"key":"bibr9-21501319231170497","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra050570"},{"key":"bibr10-21501319231170497","first-page":"147","volume":"32","author":"Abubakar M","year":"2012","journal-title":"Pak Vet J"},{"key":"bibr11-21501319231170497","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn112338-20191022-00751"},{"key":"bibr12-21501319231170497","unstructured":"Noor NA, Qazi AW, Saleem M, Masood M, Ali Z. Human brucellosis in multan. JPMA. 1986;36(11):288-289. https:\/\/jpma.org.pk\/article-details\/6094"}],"container-title":["Journal of Primary Care &amp; Community Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501319231170497","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21501319231170497","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501319231170497","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:23:59Z","timestamp":1777508639000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21501319231170497"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":12,"alternative-id":["10.1177\/21501319231170497"],"URL":"https:\/\/doi.org\/10.1177\/21501319231170497","relation":{},"ISSN":["2150-1319","2150-1327"],"issn-type":[{"value":"2150-1319","type":"print"},{"value":"2150-1327","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"article-number":"21501319231170497"}}