{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:44:08Z","timestamp":1777859048527,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Prim Care Community Health"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>This quality improvement (QI) project provided Hepatitis C virus (HCV) treatment at a Federally Qualified Health Clinic (FQHC) for persons who use illicit drugs. Many of these individuals sought treatment at the local Infectious Disease (ID) clinic but were denied care as they require a patient be drug-free for 6\u2009months prior to HCV treatment. These individuals expressed a desire to be cured of HCV, which can lead to liver failure or cirrhosis if left untreated. This project bridged the existing gap in HCV treatment that currently exists for substance-users in this city. Pre-treatment HCV levels were obtained from 20 participants who completed an 8-week daily regimen of Mavyret, a direct-acting antiviral (DAA) agent, prescribed by a primary care Nurse Practitioner (NP), trained to treat HCV. Pre-treatment HCV loads were compared to the sustained viral load, obtained 12\u2009weeks post-treatment (SVR-12), which is considered the \u201ctest of cure.\u201d The results indicate that 100% of returning patients were considered cured of HCV. This program successfully integrated HCV treatment at a community health center, in a population affected by substance use. Adoption of similar programs in primary care clinics can help meet the clinical needs of this often stigmatized and vulnerable population as well as cure them of HCV.<\/jats:p>","DOI":"10.1177\/21501319231186355","type":"journal-article","created":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T03:28:00Z","timestamp":1688959680000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Providing Hepatitis C Treatment Locally for Substance-Using Patients"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7310-6973","authenticated-orcid":false,"given":"Susan B.","family":"Clapp","sequence":"first","affiliation":[{"name":"Community Access Network, Lynchburg, VA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher B.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Community Access Network, Lynchburg, VA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,7,10]]},"reference":[{"key":"bibr1-21501319231186355","unstructured":"CDC. Hepatitis C information. Centers for Disease Control and Prevention. 2019. Accessed May 15, 2022. https:\/\/www.cdc.gov\/hepatitis\/hcv\/index.htm"},{"key":"bibr2-21501319231186355","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit306"},{"key":"bibr3-21501319231186355","unstructured":"HCV Guidance. 2022. When and in whom to initiate HCV therapy. https:\/\/www.hcvguidelines.org. https:\/\/www.hcvguidelines.org\/evaluate\/when-whom"},{"key":"bibr4-21501319231186355","doi-asserted-by":"publisher","DOI":"10.1177\/1178633719841381"},{"key":"bibr5-21501319231186355","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-019-7604-5"},{"key":"bibr6-21501319231186355","unstructured":"Federal Drug Administration. Hepatitis bulletin. 2020. Accessed June 11, 2021. https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2015\/205834s001lbl.pdf"},{"key":"bibr7-21501319231186355","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/8434602"},{"key":"bibr8-21501319231186355","doi-asserted-by":"publisher","DOI":"10.1097\/mcg.0000000000000151"},{"key":"bibr9-21501319231186355","doi-asserted-by":"publisher","DOI":"10.1080\/08870446.2015.1012195"},{"key":"bibr10-21501319231186355","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz546"},{"key":"bibr11-21501319231186355","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2019.102633"},{"key":"bibr12-21501319231186355","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-018-9873-y"},{"key":"bibr13-21501319231186355","doi-asserted-by":"publisher","DOI":"10.7326\/m17-0118"},{"key":"bibr14-21501319231186355","doi-asserted-by":"publisher","DOI":"10.1111\/add.14393"}],"container-title":["Journal of Primary Care &amp; Community Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501319231186355","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21501319231186355","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501319231186355","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:24:07Z","timestamp":1777508647000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21501319231186355"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":14,"alternative-id":["10.1177\/21501319231186355"],"URL":"https:\/\/doi.org\/10.1177\/21501319231186355","relation":{},"ISSN":["2150-1319","2150-1327"],"issn-type":[{"value":"2150-1319","type":"print"},{"value":"2150-1327","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"article-number":"21501319231186355"}}