{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:44:24Z","timestamp":1777859064348,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Research and Innovation Council, NWWI region, Mayo Clinic Health System"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Prim Care Community Health"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>The following describes a case of isolated visceral angioedema related to an angiotensin II receptor blocker (ARB) medication. Additionally, we discuss the pathophysiology of drug-induced angioedema, various presentations that can be encountered, and the leading theorized mechanisms of how renin-angiotensin-aldosterone system (RAAS) blocking medications lead to angioedema. The goal of sharing this case is to help increase awareness of the possibility of ARB-induced angioedema and to recommend keeping visceral angioedema as part of the differential diagnosis when presented with a patient who is taking an angiotensin converting enzyme inhibitor (ACEI) or ARB medication that is experiencing gastrointestinal symptoms of unclear etiology.<\/jats:p>","DOI":"10.1177\/21501319231213744","type":"journal-article","created":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T04:38:57Z","timestamp":1700023137000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["A Rare Case of Losartan-Induced Visceral Angioedema"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8324-3144","authenticated-orcid":false,"given":"Steven","family":"Rosas","sequence":"first","affiliation":[{"name":"Mayo Clinic Health System, Menomonie, WI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Austin","family":"Fowler","sequence":"additional","affiliation":[{"name":"University of Minnesota Medical School, Minneapolis, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Stodgill","sequence":"additional","affiliation":[{"name":"Mayo Clinic Health System, Menomonie, WI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6446-630X","authenticated-orcid":false,"given":"Mark","family":"Deyo-Svendsen","sequence":"additional","affiliation":[{"name":"Mayo Clinic Health System, Menomonie, WI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Phillips","sequence":"additional","affiliation":[{"name":"Mayo Clinic Health System, Menomonie, WI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,11,15]]},"reference":[{"key":"bibr1-21501319231213744","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.1598"},{"key":"bibr2-21501319231213744","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.78a.10102"},{"key":"bibr3-21501319231213744","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2019.106081"},{"key":"bibr4-21501319231213744","doi-asserted-by":"publisher","DOI":"10.3402\/jchimp.v4.25260"},{"key":"bibr5-21501319231213744","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-011-0238-z"},{"key":"bibr6-21501319231213744","doi-asserted-by":"publisher","DOI":"10.1007\/s13244-014-0329-1"},{"key":"bibr7-21501319231213744","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)60151-2"},{"key":"bibr8-21501319231213744","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)60288-8"}],"container-title":["Journal of Primary Care &amp; Community Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501319231213744","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21501319231213744","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501319231213744","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:24:20Z","timestamp":1777508660000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21501319231213744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":8,"alternative-id":["10.1177\/21501319231213744"],"URL":"https:\/\/doi.org\/10.1177\/21501319231213744","relation":{},"ISSN":["2150-1319","2150-1327"],"issn-type":[{"value":"2150-1319","type":"print"},{"value":"2150-1327","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"article-number":"21501319231213744"}}