{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:43:31Z","timestamp":1777859011441,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Reckitt Benckiser Healthcare Limited, Hull, United Kingdom"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Prim Care Community Health"],"published-print":{"date-parts":[[2025,7]]},"abstract":"\n Background:<\/jats:title>\n Proton pump inhibitors (PPIs) are frequently prescribed in primary care, often for durations that exceed guideline recommendations. We evaluated whether a digital point\u2011of\u2011prescription educational intervention based on the updated March 2023 Deutsche Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) GERD guideline could influence the prescribing patterns of primary care physicians (PCPs).<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n We conducted a 12\u2011month retrospective cohort study using anonymized prescription data from PCPs in Germany. Intervention physicians (n\u2009=\u2009886) received EMR\u2011integrated pop\u2011up messages with guideline\u2011based recommendations and optional links to further content on the \u201cPraxiswelt\u201d (Practice World) educational platform. A matched control group (n\u2009=\u2009886) received no messages. Physician engagement (click rates), PPI prescription volume, pack size, and use of ICD\u201110 diagnosis codes were compared pre\u2011 (Q2-Q4 2022) and post\u2011guideline (Q2-Q4 2023). Analyses were descriptive.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n A total of 31\u2009629 pop\u2011ups were displayed (mean\u202f37.7\u2009per physician); of these, 32.7% generated positive interactions, 0.4% negative, and 66.9% no interaction. PPI prescription volume changed by \u22122.8% in the intervention group versus +0.7% in controls. Most prescriptions exceeded the recommended 8\u2011week duration (91%-100%). ICD\u201110 coding rates remained low (missing codes: intervention 75.2% pre-guideline vs 76.7% post-guideline; controls 90.0% vs 88.1%).<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Digital pop\u2011up education at the point of prescription produced only minimal changes in prescribing volume and coding behavior. The limited effect may reflect alert fatigue, passive content, and single\u2011channel delivery. Future strategies should combine point\u2011of\u2011prescription alerts with interactive decision support, audit and feedback, and system\u2011level changes to improve both adherence and documentation.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/21501319251371385","type":"journal-article","created":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T01:01:35Z","timestamp":1760835695000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Digital Proton Pump Inhibitor Prescribing Education at The Point of Prescription: A Real-World Study in a Primary Care Setting"],"prefix":"10.1177","volume":"16","author":[{"given":"Joshua","family":"Wray","sequence":"first","affiliation":[{"name":"Reckitt Benckiser Healthcare Limited, Hull, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fergus","family":"deGrey-Warter","sequence":"additional","affiliation":[{"name":"Reckitt Benckiser Healthcare Limited, Hull, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erzsebet","family":"Horvath","sequence":"additional","affiliation":[{"name":"Reckitt Benckiser Healthcare Limited, Hull, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Haering","sequence":"additional","affiliation":[{"name":"Reckitt Benckiser, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0743-9978","authenticated-orcid":false,"given":"Patricia","family":"Aluko","sequence":"additional","affiliation":[{"name":"Reckitt Benckiser Healthcare Limited, Hull, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2124-7227","authenticated-orcid":false,"given":"Karel","family":"Kostev","sequence":"additional","affiliation":[{"name":"IQVIA, Epidemiology, Frankfurt am Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Plehhova","sequence":"additional","affiliation":[{"name":"Reckitt Benckiser Healthcare Limited, Hull, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,10,18]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-023-03534-z"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-121265"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.13023"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-83321-7"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/10600280241273773"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/21501319231221002"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.14740\/gr1238"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-2060-1069"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2021.12.247"},{"issue":"5","key":"e_1_3_3_11_2","first-page":"354","article-title":"Deprescribing proton pump inhibitors: evidence-based clinical practice guideline","volume":"63","author":"Farrell B","year":"2017","unstructured":"Farrell B, Pottie K, Thompson W, et al. Deprescribing proton pump inhibitors: evidence-based clinical practice guideline. Can Fam Physician. 2017;63(5):354-364.","journal-title":"Can Fam Physician"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39406.449456.BE"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/jcpt.13395"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12875-024-02459-5"}],"container-title":["Journal of Primary Care & Community Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501319251371385","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21501319251371385","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501319251371385","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:23:30Z","timestamp":1777508610000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21501319251371385"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":13,"alternative-id":["10.1177\/21501319251371385"],"URL":"https:\/\/doi.org\/10.1177\/21501319251371385","relation":{},"ISSN":["2150-1319","2150-1327"],"issn-type":[{"value":"2150-1319","type":"print"},{"value":"2150-1327","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]},"article-number":"21501319251371385"}}