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Eligible patients were \u226550-year-old, with no recent CRC screening, were randomised (1:1) into control (standard recommendations) or intervention (stratified risk) groups. Follow-ups at 1 and 6 months assessed screening uptake; feasibility were evaluated through surveys. In-depth interviews were conducted with patients and their Primary Care Physicians (PCPs) to assess acceptability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Response rate of patients was 56.6%. Median age was 62.5 years. Overall, the intervention group had higher CRC screening uptake (63.3%) than control group (33.3%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .022) with use of the RPT. The tool was reported by patients to be easy to use (93.3%), questions were easy to understand (100%), words easy to see (93.3%). Logistic regression associated post-secondary education with reduced need for assistance (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .042). The RPT was acceptable to patients and PCPs. Patients\u2019 perceived barriers included burdensome procedure, cost and lack of knowledge. Facilitators included intrinsic motivation and perceived early detection benefits. PCPs recognised patients\u2019 pre-determined mindset and fear of receiving bad news as barriers to screening. Education, patient empowerment and integration of RPT into workflow may aid adoption.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Risk stratification of CRC using a RPT showed increased screening uptake. Future research is needed to understand which components of this complex intervention worked to bring about improved outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21501319251397205","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T06:08:01Z","timestamp":1765519681000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Assessing the Feasibility and Acceptability of a Colorectal Cancer Risk Prediction Tool in Primary Care to Increase Screening Uptake in Singapore: A Multi-Methods Pilot Study"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3926-6354","authenticated-orcid":false,"given":"Rose Wai-Yee","family":"Fok","sequence":"first","affiliation":[{"name":"Cancer Genetics Service, Division of Medical Oncology, National Cancer Centre Singapore, Singapore"},{"name":"SingHealth Polyclinics, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sze Wern","family":"Lim","sequence":"additional","affiliation":[{"name":"SingHealth Polyclinics, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhana","family":"Letchimy","sequence":"additional","affiliation":[{"name":"SingHealth Polyclinics, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianbang","family":"Chiang","sequence":"additional","affiliation":[{"name":"Cancer Genetics Service, Division of Medical Oncology, National Cancer Centre Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0046-3518","authenticated-orcid":false,"given":"Jeanette","family":"Yuen","sequence":"additional","affiliation":[{"name":"Cancer Genetics Service, Division of Medical Oncology, National Cancer Centre Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffany Qing","family":"Lim","sequence":"additional","affiliation":[{"name":"Cancer Genetics Service, Division of Medical Oncology, National Cancer Centre Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi Yang","family":"Chua","sequence":"additional","affiliation":[{"name":"Cancer Genetics Service, Division of Medical Oncology, National Cancer Centre Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun Zi","family":"Liong","sequence":"additional","affiliation":[{"name":"Clinical Trials &amp; Epidemiological Sciences, SingHealth Group, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace Meijuan","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Supportive &amp; Palliative Care, National Cancer Centre Singapore"},{"name":"Saw Swee Hock School of Public Health - NUS, Singapore"},{"name":"Lien Centre for Palliative Care, Duke-NUS Medical School Programme for Health Services and Systems Research, Duke-NUS Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5946-1149","authenticated-orcid":false,"given":"Ngiap Chuan","family":"Tan","sequence":"additional","affiliation":[{"name":"SingHealth Polyclinics, Singapore"},{"name":"SingHealth Duke-NUS Family Medicine Academic Clinical Program, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eng Sing","family":"Lee","sequence":"additional","affiliation":[{"name":"National Healthcare Group Polyclinics, NHG Health, Singapore"},{"name":"Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne","family":"Ngeow","sequence":"additional","affiliation":[{"name":"Cancer Genetics Service, Division of Medical Oncology, National Cancer Centre Singapore, Singapore"},{"name":"Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,11]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tranon.2021.101174"},{"key":"e_1_3_3_3_2","unstructured":"Cancer Registry - National Registry of Diseases Office. 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