{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T07:05:58Z","timestamp":1779606358250,"version":"3.53.1"},"reference-count":32,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100008577","name":"Finnish research foundations","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008577","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Onni ja Hilja Tuovisen s\u00e4\u00e4ti\u00f6 sr"},{"name":"Avohoidon tutkimuss\u00e4\u00e4ti\u00f6"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Prim Care Community Health"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:p>Elderly people with chronic diseases are at risk for having severe COVID-19 disease. We were interested whether the drugs prescribed for the chronic diseases are associated with lower mortality in COVID-19 patients.<\/jats:p>\n                  <jats:p>We used Finnish national registry data for analysis of potential associations of 73 prescription drugs to mortality among 6082 adult COVID-19 patients between 1.1.2020 and 30.6.2020, before COVID-19 vaccinations were available. Adjusted odds ratios (aORs) with 95 percent confidence intervals (95% CIs) for different medications are presented.<\/jats:p>\n                  <jats:p>The use of three cardiovascular drugs was associated with lower 30 days all-cause mortality rate: candesartan (aOR 0.34, 95% CI 0.16-0.72, p=0.005), metoprolol (aOR 0.37, 95% CI 0.16-0.88, p=0.024) and rosuvastatin (aOR 0.44, 95% CI 0.21-0.94, p=0.034).<\/jats:p>\n                  <jats:p>In conclusion, COVID-19 patients who used cardiovascular drugs candesartan, metoprolol or rosuvastatin have lower 30 days all-cause mortality than other COVID-19 patients.<\/jats:p>","DOI":"10.1177\/21501319261453019","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T06:51:41Z","timestamp":1779432701000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Candesartan, Metoprolol and Rosuvastatin Associated to Lower 30-Days Mortality in Adult COVID-19 Patients \u2013 A Register Study in Finland before COVID-19 Vaccines"],"prefix":"10.1177","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9060-7193","authenticated-orcid":false,"given":"Anna","family":"Hyv\u00e4rinen","sequence":"first","affiliation":[{"name":"Tampere University Hospital"},{"name":"Wellbeing Services County of Pirkanmaa"},{"name":"Tampere University"},{"name":"L\u00e4nsi-Pohja Central Hospital"},{"name":"Wellbeing Services County of Lapland"},{"name":"Oulu University Hospital"},{"name":"Wellbeing Services County of Northern Ostrobothnia"},{"name":"University of Oulu"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mika","family":"Helminen","sequence":"additional","affiliation":[{"name":"Tampere University"},{"name":"Tampere University Hospital"},{"name":"Wellbeing Services County of Pirkanmaa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markku","family":"Broas","sequence":"additional","affiliation":[{"name":"L\u00e4nsi-Pohja Central Hospital"},{"name":"Wellbeing Services County of Lapland"},{"name":"Lapland Central Hospital"},{"name":"Wellbeing Services County of Lapland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannu","family":"Syrj\u00e4l\u00e4","sequence":"additional","affiliation":[{"name":"Oulu University Hospital"},{"name":"Wellbeing Services County of Northern 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