{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:43:00Z","timestamp":1777858980934,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"canadian institutes of health research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Prim Care Community Health"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Lyme Disease (LD) is the most common tick-borne disease in North America. With the number of cases increasing yearly, Canadian healthcare professionals (HCP) rely on up-to-date and evidence-informed guidelines, instruction, and resources to effectively prevent, diagnose, and treat Lyme disease (LD). This review is the first of its kind to examine gray literature and analyze the diversity of recommendations provided to Canadian HCP about the prevention, diagnosis, and treatment of Lyme disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A gray literature review consisting of 4 search strategies was conducted to retrieve materials targeted to Canadian HCP. Searches within targeted websites, targeted Google searches, and gray literature databases, and consultation with content experts were done to look for continuing medical education (CME) events, clinical flow charts, webinars, videos, and reference documents that discussed the prevention, diagnosis, and treatment of Lyme disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 115 resources were included in this study. Recommendations surrounding prevention strategies were less varied between materials, whereas diagnosis and treatment recommendations were more varied. Our findings suggest that Canadian HCP are met with varying and sometimes contradictory recommendations for diagnosing and treating LD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Due to the increasing incidence of LD in Canada, there is a greater need for resource consistency. Providing this consistency may help mitigate LD burden, standardize approaches to prevention, diagnosis and treatment, and improve patient outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/21501327211050744","type":"journal-article","created":{"date-parts":[[2021,10,16]],"date-time":"2021-10-16T03:59:06Z","timestamp":1634356746000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Lyme Disease Training and Knowledge Translation Resources Available to Canadian Healthcare Professionals: A Gray Literature Review"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2026-1051","authenticated-orcid":false,"given":"Angela M.","family":"Coderre-Ball","sequence":"first","affiliation":[{"name":"Queen\u2019s University, Kingston, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sania","family":"Sahi","sequence":"additional","affiliation":[{"name":"Queen\u2019s University, Kingston, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Anthonio","sequence":"additional","affiliation":[{"name":"Queen\u2019s University, Kingston, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madison","family":"Roberston","sequence":"additional","affiliation":[{"name":"Queen\u2019s University, Kingston, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rylan","family":"Egan","sequence":"additional","affiliation":[{"name":"Queen\u2019s University, Kingston, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,10,15]]},"reference":[{"key":"bibr1-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1093\/jme\/tjw103"},{"key":"bibr2-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.90"},{"key":"bibr3-21501327211050744","unstructured":"Government of Canada. Surveillance of Lyme disease. 2020. Accessed November 17, 2020. https:\/\/www.canada.ca\/en\/public-health\/services\/diseases\/lyme-disease\/surveillance-lyme-disease.html"},{"key":"bibr4-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1016\/j.cll.2010.01.003"},{"key":"bibr5-21501327211050744","unstructured":"Government of Canada. For health professionals: Lyme disease. 2018. Accessed December 14, 2020. https:\/\/www.canada.ca\/en\/public-health\/services\/diseases\/lyme-disease\/health-professionals-lyme-disease.html"},{"key":"bibr6-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-018-3417-1"},{"key":"bibr7-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyi129"},{"key":"bibr8-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200107123450202"},{"key":"bibr9-21501327211050744","doi-asserted-by":"publisher","DOI":"10.5114\/reum.2015.50557"},{"key":"bibr10-21501327211050744","volume-title":"Clinical protocol: \u201cChronic Lyme disease\u201d or \u201cpost-Lyme syndrome\u201d","author":"BC Women\u2019s Hospital + Health Centre","year":"2020"},{"key":"bibr11-21501327211050744","unstructured":"International Lyme and Associated Diseases Society. Controversies and challenges. ILADS. 2020. Accessed December 11, 2020. https:\/\/www.ilads.org\/research-literature\/controversies-challenges\/"},{"key":"bibr12-21501327211050744","unstructured":"Centre for Effective Practice. Early Lyme Disease Management in Primary Care. 2020. Accessed July 12, 2021. https:\/\/cep.health\/media\/uploaded\/CEP_EarlyLymeDisease_Provider_2020.pdf"},{"key":"bibr13-21501327211050744","unstructured":"Morrow G, Karam F. Lyme Disease, From Diagnosis to Treatment, at the Localized and Disseminated Stages. Report in Support of Knowledge Transfer Tools for Diagnosis and Treatment. Institut national d\u2019excellence en sant\u00e9 et an services sociaux (INESS); 2019. Accessed July 12, 2021. https:\/\/www.inesss.qc.ca\/fileadmin\/doc\/INESSS\/Rapports\/Biologie_medicale\/Lyme_Diag-traitement\/inesss_report-lyme-rx-dx.pdf"},{"key":"bibr14-21501327211050744","doi-asserted-by":"publisher","DOI":"10.5864\/d2019-006"},{"key":"bibr15-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12669"},{"key":"bibr16-21501327211050744","unstructured":"Library of University of Toronto. Grey literature \u2013 searching the literature: a guide to comprehensive searching in the health sciences. 2019. Accessed September 15, 2019. https:\/\/guides.library.utoronto.ca\/c.php?g=577919&p=4123572"},{"key":"bibr17-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-015-0125-0"},{"key":"bibr18-21501327211050744","unstructured":"CLyDRN. Canadian Lyme disease research network | About the network. 2019. Accessed January 22, 2021. https:\/\/www.clydrn.ca\/about-the-network\/"},{"key":"bibr19-21501327211050744","doi-asserted-by":"publisher","DOI":"10.3316\/QRJ0902027"},{"key":"bibr20-21501327211050744","unstructured":"NVivo. Learn more about data analysis software. 2021. Accessed January 23, 2021. https:\/\/www.qsrinternational.com\/nvivo-qualitative-data-analysis-software\/about\/nvivo"},{"key":"bibr21-21501327211050744","unstructured":"Hatchette TF. The diagnosis and management of Lyme disease in Nova Scotia. 2019. Accessed December 14, 2020. https:\/\/cdn.dal.ca\/content\/dam\/dalhousie\/pdf\/faculty\/medicine\/departments\/core-units\/cpd\/CHP\/Lyme.pdf"},{"key":"bibr22-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1177\/2374373517736385"},{"key":"bibr23-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2296-15-79"},{"key":"bibr24-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1111\/j.0737-1209.2006.230104.x"},{"key":"bibr25-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1080\/14635240.2021.1920045"},{"key":"bibr26-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1001\/amajethics.2018.1052"},{"key":"bibr27-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1002\/chp.21290"},{"key":"bibr28-21501327211050744","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.12175"},{"issue":"7","key":"bibr29-21501327211050744","first-page":"491","volume":"39","author":"Ventola CL","year":"2014","journal-title":"Pharmacol Ther"}],"container-title":["Journal of Primary Care &amp; Community Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501327211050744","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/21501327211050744","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/21501327211050744","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:23:03Z","timestamp":1777508583000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/21501327211050744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":29,"alternative-id":["10.1177\/21501327211050744"],"URL":"https:\/\/doi.org\/10.1177\/21501327211050744","relation":{},"ISSN":["2150-1319","2150-1327"],"issn-type":[{"value":"2150-1319","type":"print"},{"value":"2150-1327","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]},"article-number":"21501327211050744"}}